Linde-Zwirble Walter T, Angus Derek C
The CRISMA Laboratory (Clinical Research, Investigation, and Systems Modeling of Acute Illness), University of Pittsburgh, Pittsburgh, PA, USA.
Crit Care. 2004 Aug;8(4):222-6. doi: 10.1186/cc2917. Epub 2004 Jul 9.
Three new articles in Critical Care add to an expanding body of information on the epidemiology of severe sepsis. Although there have been a range of approaches to estimate the incidence of severe sepsis, most studies report severe sepsis in about 10 +/- 4% of ICU patients with a population incidence of 1 +/- 0.5 cases per 1000. Importantly, the availability of ICU services may well determine the number of treated cases of severe sepsis, and it seems clear that these studies are reporting the treated incidence, not the incidence, of severe sepsis. In the future, we must focus on whether all severe sepsis should be treated, and, consequently, what level of ICU services is optimal.
《重症监护》杂志上发表的三篇新文章，进一步丰富了有关严重脓毒症流行病学的信息。尽管有一系列方法用于估算严重脓毒症的发病率，但大多数研究报告称，在入住重症监护病房（ICU）的患者中，约10%±4%发生严重脓毒症，总体发病率为每1000人中有1±0.5例。重要的是，ICU服务的可及性很可能决定了严重脓毒症的治疗病例数，而且很明显，这些研究报告的是严重脓毒症的治疗发病率，而非发病率。未来，我们必须关注是否所有严重脓毒症都应接受治疗，以及相应地，何种水平的ICU服务才是最佳的。
