Ribeiro José C, Guerra Sandra, Oliveira José, Teixeira-Pinto António, Twisk Jos W R, Duarte José A, Mota Jorge
Research Centre in Physical Activity, Health and Leisure, Faculty of Sports Science and Physical Education, University of Porto, Porto 4200 450, Portugal.
Prev Med. 2004 Sep;39(3):596-601. doi: 10.1016/j.ypmed.2004.02.023.
From a preventive point of view, it is especially important to investigate the life style risk factors connected to cardiovascular disease (CVD) biological risk factors clustering. The purposes of this study were (I) to determine in pediatric population the coexistence of biological cardiovascular disease risk factors (high blood pressure (HBP), percentage of high fat mass (%HFM), and high total cholesterol (HTC)) and (II) to study the relationship between low physical activity, a lifestyle risk factor, with those biological risk factors.
This study comprised 1461 children (699 males and 762 females) aged between 8 and 15 years old. The following measurements were carried out: blood pressure, percentage of fat mass, total cholesterol (TC), and physical activity. The quartiles, adjusted for age and gender, were the criterion used to classify the subjects at risk. Odds ratios and confidence intervals at 95% were used to study HBP, HTC, and %HFM clustering in both genders. Multinomial logistic regression was used to investigate the relationship between clustering and physical activity index (PAI).
The findings of this study indicated that there is clustering for the biological risk factors, specially between HBP and %HFM for females. It can be observed that about half of the subjects had at least one biological risk factor.
The results of the present study suggest that children and adolescents with higher PAI have a lower number of biological risk factors for CVD.
从预防的角度来看,调查与心血管疾病(CVD)生物危险因素聚集相关的生活方式风险因素尤为重要。本研究的目的是:(I)确定儿科人群中心血管疾病生物危险因素(高血压(HBP)、高脂肪质量百分比(%HFM)和高总胆固醇(HTC))的共存情况;(II)研究低体力活动(一种生活方式风险因素)与这些生物危险因素之间的关系。
本研究纳入了1461名年龄在8至15岁之间的儿童(699名男性和762名女性)。进行了以下测量:血压、脂肪质量百分比、总胆固醇(TC)和体力活动。根据年龄和性别调整后的四分位数是用于对有风险的受试者进行分类的标准。使用95%的优势比和置信区间来研究男女中HBP、HTC和%HFM的聚集情况。使用多项逻辑回归来研究聚集与体力活动指数(PAI)之间的关系。
本研究结果表明,生物危险因素存在聚集现象,特别是女性中HBP和%HFM之间。可以观察到,约一半的受试者至少有一个生物危险因素。
本研究结果表明,PAI较高的儿童和青少年患CVD的生物危险因素数量较少。