用于纳米技术应用的自组装肽和蛋白质。

Self-assembling peptides and proteins for nanotechnological applications.

作者信息

Rajagopal Karthikan, Schneider Joel P

机构信息

Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, USA.

出版信息

Curr Opin Struct Biol. 2004 Aug;14(4):480-6. doi: 10.1016/j.sbi.2004.06.006.

DOI:10.1016/j.sbi.2004.06.006

PMID:15313243

Abstract

Photolithography enables the precise construction of nanodevices in two-dimensional formats. However, self-assembly of designed molecules serves as an alternative for the construction of three-dimensional nanoscale systems and is particularly appealing in that material properties can potentially be engineered at the molecular level. Peptides and proteins hold promise as building blocks for self-assembled systems because of their exquisite three-dimensional structures and evolutionarily fine-tuned functions.

摘要

光刻技术能够精确构建二维形式的纳米器件。然而，设计分子的自组装是构建三维纳米系统的一种替代方法，特别吸引人的是，材料特性有可能在分子水平上进行设计。肽和蛋白质有望成为自组装系统的构建模块，因为它们具有精致的三维结构和经过进化微调的功能。