Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669.
Trends Biotechnol. 2012 Mar;30(3):155-65. doi: 10.1016/j.tibtech.2011.11.001. Epub 2011 Dec 22.
Short, self-assembling peptides form a variety of stable nanostructures used for the rational design of functional devices. Peptides serve as organic templates for conjugating biorecognition elements, and assembling ordered nanoparticle arrays and hybrid supramolecular structures. We are witnessing the emergence of a new phase of bionanotechnology, particularly towards electronic, photonic and plasmonic applications. Recent advances include self-assembly of photoluminescent semiconducting nanowires and peptide-conjugated systems for sensing, catalysis and energy storage. Concurrently, methods and tools have been developed to control and manipulate the self-assembled nanostructures. Furthermore, there is growing knowledge on nanostructure properties such as piezoelectricity, dipolar electric field and stability. This review focuses on the emerging role of short, linear self-assembling peptides as simple and versatile building blocks for nanodevices.
短的、自组装的肽形成了多种稳定的纳米结构，用于功能器件的合理设计。肽可用作连接生物识别元件的有机模板，并组装有序的纳米粒子阵列和混合超分子结构。我们正在见证生物纳米技术的一个新阶段的出现，特别是在电子、光子和等离子体应用方面。最近的进展包括光致发光半导体纳米线的自组装和用于传感、催化和能量存储的肽键合系统。同时，也开发了控制和操纵自组装纳米结构的方法和工具。此外，人们对纳米结构的特性（如压电性、偶极电场和稳定性）有了更多的了解。这篇综述重点介绍了短的、线性自组装肽作为纳米器件的简单而通用的构建块的新兴作用。
