Lin Danny Y, Manche Edward E
Department of Ophthalmology, Stanford University Medical Center, 900 Blake Wilbur Drive, Stanford, CA 94304, USA.
J Cataract Refract Surg. 2004 Aug;30(8):1675-84. doi: 10.1016/j.jcrs.2003.12.052.
To evaluate the custom-contoured ablation pattern (C-CAP) method as a tool for providing customized laser ablations for decentered ablations based on corneal topography data.
Department of Ophthalmology, Stanford University, Stanford, California, USA.
In a prospective noncomparative interventional case series, 8 eyes from 7 post-laser in situ keratomileusis (LASIK) patients and 1 post-photorefractive keratectomy (PRK) patient with symptomatic laser decentration were treated with the C-CAP method. The Zeiss Humphrey topography system was used to identify and analyze decentered ablations. The computer software allowed the surgeon to preoperatively model the effect of various ablation schemes on the preoperative topography until a scheme that alleviated the decentration was identified. The planned ablation parameters, which included size, depth, and location of the ablation, were programmed into the Visx S4 excimer laser before treatment.
The mean follow-up after C-CAP ablation was 4.2 months (range 1.8 to 6.3 months). At the last postoperative examination, no eye lost a line of best spectacle-corrected visual acuity (BSCVA). The uncorrected visual acuity (UCVA) improved by 3 lines in 1 eye (12.5%), by 2 lines in 1 eye (12.5%), and by 1 line in 3 eyes (37.5%); it remained unchanged in 2 eyes (25.0%) and decreased by 1 line in 1 eye (12.5%). The BSCVA improved by 3 lines in 1 eye (12.5%), by 2 lines in 2 eyes (25.0%), and by 1 line in 3 eyes (37.5%); it remained unchanged in 2 eyes (25.0%). In all eyes, including those without improvement in UCVA or BSCVA, a significant improvement in centration and subjective complaints was achieved. The pre-C-CAP and post-C-CAP root-mean-square (RMS) wavefront data were available in 5 of 8 eyes. The total and higher-order RMS aberrations decreased by 41.7% (P =.0027) and 45.5% (P =.039), respectively, after C-CAP treatment.
Early U.S. results show the topography-driven C-CAP method is an effective tool to address untreatable postsurgical decentration. This method is presented as a technique to enhance the overall quality of vision, reduce patient-perceived visual aberrations, regularize the corneal surface, and maximize BSCVA.
评估定制轮廓消融模式(C-CAP)方法,作为一种基于角膜地形图数据为偏心消融提供定制激光消融的工具。
美国加利福尼亚州斯坦福大学眼科系。
在一项前瞻性非对比性介入病例系列研究中,对7例准分子原位角膜磨镶术(LASIK)术后患者和1例有症状的激光屈光性角膜切削术(PRK)术后患者的8只眼进行了C-CAP方法治疗,这些患者存在激光偏心现象。使用蔡司汉弗莱地形图系统识别和分析偏心消融。计算机软件允许外科医生在术前模拟各种消融方案对术前地形图的影响,直到确定一种减轻偏心的方案。在治疗前,将计划的消融参数(包括消融的大小、深度和位置)编程到威视S4准分子激光中。
C-CAP消融术后平均随访时间为4.2个月(范围1.8至6.3个月)。在最后一次术后检查时,没有一只眼睛丧失最佳矫正视力(BSCVA)的一行。1只眼(12.5%)的裸眼视力(UCVA)提高了3行,1只眼(12.5%)提高了2行,3只眼(37.5%)提高了1行;2只眼(25.0%)保持不变,1只眼(12.5%)下降了1行。1只眼(12.5%)的BSCVA提高了3行,2只眼(25.0%)提高了2行,3只眼(37.5%)提高了1行;2只眼(25.0%)保持不变。在所有眼中,包括那些UCVA或BSCVA没有改善的眼睛,在对中情况和主观症状方面都有显著改善。8只眼中有5只眼可获得C-CAP治疗前和治疗后的均方根(RMS)波前数据。C-CAP治疗后,总RMS像差和高阶RMS像差分别下降了41.7%(P = 0.0027)和45.5%(P = 0.039)。
美国早期结果表明,地形引导的C-CAP方法是解决无法治疗的术后偏心问题的有效工具。该方法被提出作为一种提高整体视觉质量、减少患者感知的视觉像差、使角膜表面规则化并最大化BSCVA的技术。