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子宫内膜息肉恶变的频率是多少?

How often are endometrial polyps malignant?

作者信息

Shushan Asher, Revel Ariel, Rojansky Nathan

机构信息

Department of Obstetrics and Gynecology, Hadassah University Hospital, PO Box 12000, Jerusalem 91120, Israel.

出版信息

Gynecol Obstet Invest. 2004;58(4):212-5. doi: 10.1159/000080189. Epub 2004 Aug 12.

Abstract

OBJECTIVE

Endometrial polyps are a frequent pathology encountered during pelvic sonography and diagnostic hysteroscopies. The true incidence of malignant endometrial polyps is unknown. The estimations range from 0.5 to 4.8%. The objective of this study was to investigate the frequency of malignant endometrial polyps, and to characterize the hysteroscopic image of these polyps.

METHODS

The study included 300 consecutive women with endometrial polyps who underwent hysteroscopic polypectomy. Patients' characteristics, operative findings, and pathology reports were analyzed.

RESULTS

Four of the 300 endometrial polyps removed by operative hysteroscopy were malignant (1.3%). Patients with malignant polyps were symptomatic peri- or postmenopausal women. All asymptomatic polyps in this series were found to be benign. We could not identify any distinct hysteroscopic feature of malignancy.

CONCLUSIONS

Our study shows that about 1.5% of endometrial polyps may be malignant. This finding reinforces the indication for removal of symptomatic endometrial polyps, preferably by a hysteroscopic procedure. The significance of asymptomatic uterine polyps has still to be determined.

摘要

目的

子宫内膜息肉是盆腔超声检查和诊断性宫腔镜检查中常见的病理情况。恶性子宫内膜息肉的真实发病率尚不清楚。估计范围为0.5%至4.8%。本研究的目的是调查恶性子宫内膜息肉的发生率,并描述这些息肉的宫腔镜图像特征。

方法

该研究纳入了300例连续接受宫腔镜息肉切除术的子宫内膜息肉患者。分析了患者的特征、手术结果和病理报告。

结果

300例经手术宫腔镜切除的子宫内膜息肉中有4例为恶性(1.3%)。恶性息肉患者为围绝经期或绝经后有症状的女性。本系列中所有无症状息肉均为良性。我们未能识别出任何明显的恶性宫腔镜特征。

结论

我们的研究表明,约1.5%的子宫内膜息肉可能是恶性的。这一发现强化了对有症状子宫内膜息肉进行切除的指征,最好通过宫腔镜手术进行。无症状子宫息肉的意义仍有待确定。

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