Dokainish Hisham
Department of Medicine, Cardiology Section, Baylor College of Medicine, Houston, Texas 77030, USA.
Curr Opin Cardiol. 2004 Sep;19(5):437-41. doi: 10.1097/01.hco.0000131538.55528.8f.
Describe the rationale behind, and clinical use of, tissue Doppler (TD) imaging in the assessment of left ventricular (LV) diastolic function, with a focus on recent developments.
Tissue Doppler imaging is a novel echocardiographic technique that directly measures myocardial velocities. Systolic TD measurements assess left and right ventricular myocardial contractile function. Diastolic TD values reflect myocardial relaxation, and in combination with conventional Doppler measurements, ratios (E/Ea) have been developed to estimate LV filling pressures. TD values and derived ratios have been demonstrated to be valuable in the diagnosis of elevated LV filling pressures, clinical congestive heart failure (CHF), and the prognosis of patients with cardiac disease and CHF. New TD indices have now been developed to assess myocardial relaxation and LV filling pressures, and the impact of LV systolic function on the use of TD imaging has recently been described. TD echocardiography is being used in an ever-widening group of patients for the assessment of LV diastolic function, and its correlation to, and comparison with, B-type natriuretic peptide is an active area of current investigation.
This review focuses on new developments in the clinical use of TD echocardiography in the evaluation of left ventricular diastolic function.
阐述组织多普勒（TD）成像在评估左心室（LV）舒张功能方面的基本原理及临床应用，重点关注近期进展。
组织多普勒成像是一种直接测量心肌速度的新型超声心动图技术。收缩期TD测量可评估左、右心室心肌收缩功能。舒张期TD值反映心肌松弛情况，与传统多普勒测量相结合，已开发出比值（E/Ea）来估计左心室充盈压。TD值及导出的比值已被证明在诊断左心室充盈压升高、临床充血性心力衰竭（CHF）以及心脏病和CHF患者的预后方面具有重要价值。目前已开发出新的TD指标来评估心肌松弛和左心室充盈压，并且最近已描述了左心室收缩功能对TD成像应用的影响。TD超声心动图正被用于越来越广泛的患者群体以评估左心室舒张功能，其与B型利钠肽的相关性及比较是当前研究的一个活跃领域。
本综述重点关注TD超声心动图在评估左心室舒张功能临床应用方面的新进展。
