Sedov V M, Salov A B
Vestn Khir Im I I Grek. 2004;163(3):11-3.
The possible appearance of thrombotic complications of laparoscopic cholecystectomy (LCE) is one of negative consequences of the effects of carboxyl pneumoperitoneum (CPP). Risk factors of thrombogenesis were investigated in 91 patients who had been subjected to LCE and in 50 patients after open cholecystectomy. It was established that the rate of blood flow in the femoral vein after CPP was 31% lower. The creation of CPP facilitates the development of hypercoagulation. The greatest alteration occurs in the anticoagulation system of blood: "free heparin" becomes 31.7% lower, fibrinolytic activity of blood reduces by 73.1%. Prophylactics of thrombotic complications must be complex and be started with the detection of risk factors and finished with a combination of physical and pharmacological methods.
腹腔镜胆囊切除术（LCE）可能出现血栓形成并发症是二氧化碳气腹（CPP）影响的负面后果之一。对91例行LCE的患者和50例行开腹胆囊切除术的患者的血栓形成危险因素进行了研究。结果表明，CPP后股静脉血流速度降低31%。CPP的形成促进了高凝状态的发展。血液抗凝系统发生的变化最大：“游离肝素”降低31.7%，血液纤溶活性降低73.1%。血栓形成并发症的预防必须是综合性的，从危险因素的检测开始，以物理和药物方法相结合结束。
