Harper P S
Institute of Medical Genetics, University of Wales College of Medicine, Cardiff, United Kingdom.
Am J Hum Genet. 1992 Mar;50(3):460-4.
Huntington disease, one of the longest established and most serious human genetic disorders, has been the subject of considerable abuse during the present century in relation to the application of genetic knowledge, most notably in Nazi Germany but also in other countries. This disorder provides a valuable example of how abuses in the past need to be recognized and confronted, if we are to avoid their recurrence in relation to new molecular and computing techniques in genetics.
亨廷顿舞蹈症是历史最悠久、最严重的人类遗传疾病之一,在本世纪,尤其是在纳粹德国以及其他国家,它因遗传知识的应用而遭受了诸多滥用。如果我们要避免在遗传学新的分子和计算技术方面重蹈覆辙,那么这种疾病为认识和应对过去的滥用情况提供了一个宝贵的范例。