Arakelyan V B, Haroutiunian S G, Abgaryan H H, Arakelyan A V, Haroutunyan T S
Yerevan Physics Institute, Alikhanian Brothers Str.2, Yerevan, 375036 Armenia.
J Biomol Struct Dyn. 2004 Oct;22(2):245-52. doi: 10.1080/07391102.2004.10506999.
Simultaneous formulation binding and structure modification of the binding site leads to binding process that can be analyzed within the framework of the non-linear theory of dynamic systems. Such an approach allows us to obtain several properties of the binding center: plurality of stationary (stable and unstable) states at binding, recognition of bistable and hysteretic binding modes. It is also shown that adsorption centre deformation leads to a S-shaped adsorption curve.
结合位点的同时构象结合和结构修饰导致了一种结合过程，该过程可以在动态系统的非线性理论框架内进行分析。这种方法使我们能够获得结合中心的几个特性：结合时多个稳态（稳定和不稳定）状态、双稳态和滞后结合模式的识别。还表明吸附中心变形会导致S形吸附曲线。
