Bluthenthal Ricky N, Malik Mohammed Rehan, Grau Lauretta E, Singer Merrill, Marshall Patricia, Heimer Robert
Health Program and Drug Policy Research Center, RAND, Santa Monica, CA 90407-2138, USA.
Addiction. 2004 Sep;99(9):1136-46. doi: 10.1111/j.1360-0443.2004.00694.x.
Better sterile syringe access should be associated with a lower likelihood of syringe re-use and receptive syringe sharing, although few empirical studies have examined gradients in syringe access using both individual and ecological data. In this study, we compare syringe re-use and receptive syringe sharing among injection drug users (IDUs) with syringe exchange program (SEP) and legal over-the-counter pharmacy access with limits on syringes that can be purchased, exchanged or possessed to IDUs with no pharmacy sales but unlimited syringe access through SEPs. We address three questions: (1) Does residing in an area with no legal syringe possession increase the likelihood of police contact related to possessing drug paraphernalia? (2) Among direct SEP users, is use of more permissive SEPs associated with less likelihood of syringe re-use and receptive syringe sharing? (3) Among non-SEP users, is residing in an area with pharmacy access associated with lower likelihood of syringe re-use and receptive syringe sharing?
Quantitative survey of IDUs recruited from SEPs, subject nomination and outreach methods. Multivariate analyses compared police contact, syringe re-use and receptive syringe sharing among IDUs recruited in three cities.
In multivariate analyses, we found that police contact was associated independently with residing in the area with no legal possession of syringes; among SEP users, those with access to SEPs without limits had lower syringe re-use but not lower syringe sharing; and that among non-SEP users, no significant differences in injection risk were observed among IDUs with and without pharmacy access to syringes.
We found that greater legal access to syringes, if accompanied by limits on the number of syringes that can be exchanged, purchased and possessed, may not have the intended impacts on injection-related infectious disease risk among IDUs.
更好的无菌注射器获取途径应与较低的注射器重复使用及接受性注射器共用可能性相关,尽管很少有实证研究使用个体和生态数据来检验注射器获取途径的梯度差异。在本研究中,我们比较了参与注射器交换项目(SEP)且合法从非处方药店获取注射器但有购买、交换或持有数量限制的注射吸毒者(IDU)与无药店销售但通过SEP可无限制获取注射器的IDU之间的注射器重复使用及接受性注射器共用情况。我们探讨三个问题:(1)居住在无合法注射器持有地区是否会增加与持有吸毒用具相关的警方接触可能性?(2)在直接使用SEP的人群中,使用更宽松的SEP是否与较低的注射器重复使用及接受性注射器共用可能性相关?(3)在未使用SEP的人群中,居住在有药店可获取注射器的地区是否与较低的注射器重复使用及接受性注射器共用可能性相关?
对通过SEP招募、受试者提名及外展方法招募的IDU进行定量调查。多变量分析比较了在三个城市招募的IDU之间的警方接触、注射器重复使用及接受性注射器共用情况。
在多变量分析中,我们发现警方接触独立地与居住在无合法注射器持有地区相关;在使用SEP的人群中,可无限制使用SEP的人注射器重复使用较低,但注射器共用情况并未降低;并且在未使用SEP的人群中,有药店可获取注射器和无药店可获取注射器的IDU之间在注射风险方面未观察到显著差异。
我们发现,如果注射器合法获取量增加,但同时伴有可交换、购买和持有的注射器数量限制,可能不会对IDU中与注射相关的传染病风险产生预期影响。