Dry J, Pradalier A, Herman D, Leynadier F
Sem Hop. 1976;52(31-32):1691-5.
The authors review 26 cases of multiple endocrine tumours with presence of a carcinoid tumour. In 44% the carcinoid was localised to the bronchus, in 20% of cases to the small intestine or duodenum. In 76% of cases during multiple endocrine tumours, the carcinoid appeared in embryological derivatives of the anterior part of the intestine. No carcinoid syndrome was reported. The difficulty of histological distinction has led to the description of carcinoid islet cell tumours. These facts fit in with the APUD concept.
作者回顾了26例伴有类癌肿瘤的多发性内分泌肿瘤病例。44%的类癌位于支气管,20%位于小肠或十二指肠。在76%的多发性内分泌肿瘤病例中,类癌出现在肠前部的胚胎衍生物中。未报告类癌综合征。组织学鉴别困难导致了类癌胰岛细胞瘤的描述。这些事实符合APUD概念。