Vercruysse Steven, Kuiper Martin
Department of Plant Systems Biology, Flanders Interuniversity Institute for Biotechnology (VIB), Ghent University Technologiepark 927, B-9052, Gent, Belgium.
Bioinformatics. 2005 Jan 15;21(2):269-71. doi: 10.1093/bioinformatics/bth478. Epub 2004 Aug 19.
We present SIM-plex, a genetic network simulator with a very intuitive interface in which a user can easily specify interactions as simple 'if-then' statements. The simulator is based on the mathematical model of Piecewise Linear Differential Equations (PLDEs). With PLDEs, genetic interactions are approximated as acting in a switch-like manner.
The Java program, examples and a tutorial are available at http://www.psb.ugent.be/cbd/
{stcru,makui}@psb.ugent.be
我们展示了SIM-plex,这是一个具有非常直观界面的遗传网络模拟器,用户可以轻松地将相互作用指定为简单的“如果-那么”语句。该模拟器基于分段线性微分方程(PLDEs)的数学模型。对于PLDEs,遗传相互作用近似以类似开关的方式起作用。
Java程序、示例和教程可在http://www.psb.ugent.be/cbd/获取。
{stcru,makui}@psb.ugent.be