BNArray：一个用于通过贝叶斯网络从微阵列数据构建基因调控网络的R软件包。
BNArray: an R package for constructing gene regulatory networks from microarray data by using Bayesian network.
作者信息
Chen Xiaohui, Chen Ming, Ning Kaida
机构信息
Department of Bioinformatics Zhejiang University, Hangzhou 310058, China.
出版信息
Bioinformatics. 2006 Dec 1;22(23):2952-4. doi: 10.1093/bioinformatics/btl491. Epub 2006 Sep 27.
UNLABELLED
BNArray is a systemized tool developed in R. It facilitates the construction of gene regulatory networks from DNA microarray data by using Bayesian network. Significant sub-modules of regulatory networks with high confidence are reconstructed by using our extended sub-network mining algorithm of directed graphs. BNArray can handle microarray datasets with missing data. To evaluate the statistical features of generated Bayesian networks, re-sampling procedures are utilized to yield collections of candidate 1st-order network sets for mining dense coherent sub-networks.
AVAILABILITY
The R package and the supplementary documentation are available at http://www.cls.zju.edu.cn/binfo/BNArray/.
未标注
BNArray是一个用R语言开发的系统化工具。它通过使用贝叶斯网络，促进从DNA微阵列数据构建基因调控网络。利用我们扩展的有向图子网挖掘算法，重建具有高可信度的调控网络的重要子模块。BNArray可以处理存在缺失数据的微阵列数据集。为了评估生成的贝叶斯网络的统计特征，采用重采样程序来生成候选一阶网络集的集合，用于挖掘密集连贯子网。
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