McNeely Margaret L, Magee David J, Lees Alan W, Bagnall Keith M, Haykowsky Mark, Hanson John
Department of Rehabilitation Medicine, Cross Cancer Institute, Edmonton, Alberta, Canada.
Breast Cancer Res Treat. 2004 Jul;86(2):95-106. doi: 10.1023/B:BREA.0000032978.67677.9f.
The purpose of this investigation was to compare the reduction in arm lymphedema volume achieved from manual lymph drainage massage (MLD) in combination with multi-layered compression bandaging (CB) to that achieved by CB alone.
Fifty women with lymphedema (mean age of 59 years +/- 13 years) were randomly assigned to 4 weeks of combined MLD/CB or CB alone. The primary study endpoint was the reduction in arm lymphedema volume, which was determined by water displacement volumetry and measurement of circumference. Independent assessors, blinded to subject treatment assignment, performed the outcome measurements.
Arm lymphedema volume decreased significantly after 4 weeks irrespective of treatment assignment (p < 0.001). Individuals with mild lymphedema receiving combined MLD/CB had a significantly larger percentage reduction in volume compared to individuals with mild lymphedema receiving CB alone, and compared to individuals with moderate or severe lymphedema receiving either treatment.
These findings indicate that CB, with or without MLD, is an effective intervention in reducing arm lymphedema volume. The findings suggest that CB on its own should be considered as a primary treatment option in reducing arm lymphedema volume. There may be an additional benefit from the application of MLD for women with mild lymphedema; however, this finding will need to be further examined in the research setting.
本研究的目的是比较手动淋巴引流按摩(MLD)联合多层加压包扎(CB)与单纯CB在减少手臂淋巴水肿体积方面的效果。
五十名淋巴水肿女性(平均年龄59岁±13岁)被随机分配接受为期4周的MLD/CB联合治疗或单纯CB治疗。主要研究终点是手臂淋巴水肿体积的减少,通过排水体积测量法和周长测量来确定。独立评估人员在不知道受试者治疗分配的情况下进行结果测量。
无论治疗分配如何,4周后手臂淋巴水肿体积均显著下降(p < 0.001)。与单纯接受CB治疗的轻度淋巴水肿患者相比,以及与接受任何一种治疗的中度或重度淋巴水肿患者相比,接受MLD/CB联合治疗的轻度淋巴水肿患者体积减少的百分比显著更大。
这些发现表明,无论是否联合MLD,CB都是减少手臂淋巴水肿体积的有效干预措施。研究结果表明,单纯CB应被视为减少手臂淋巴水肿体积的主要治疗选择。对于轻度淋巴水肿女性,应用MLD可能有额外益处;然而,这一发现需要在研究环境中进一步研究。