Toliusiene Jolanta, Lesauskaite Vita
Department of Nursing and Care, Kaunas University of Medicine, Kaunas, Lithuania.
Support Care Cancer. 2004 Oct;12(10):716-9. doi: 10.1007/s00520-004-0635-0.
Our aim was to study the nutritional status of older men receiving treatment for advanced prostate cancer (PC).
We assessed 80 patients: 40 patients with advanced PC (research group) and 40 with benign prostatic hyperplasia (BPH) (control group). The instruments used were: Mini Nutritional Assessment (MNA) and the Yesavage Geriatric Depression Scale (GDS)-Short Form. Complementary questions were asked reflecting nutritional status.
Mean age of PC patients was 72 (65-94) years and that of control group 71 (65-85) years. Patients with PC had rapid weight loss--15 (39.5%) of patients lost more than 3 kg over 3 months. Depressive symptomatology was more common in the research group (p<0.05), and it was inversely correlated with nutrition. Age had no influence on symptoms of depression. Digestive disorders troubled 23 (57.5%) of the research group and 14 (20%) of the control group. Digestive troubles had an influence on appetite in both groups t=0.54 and r=0.46 (p<0.05). No patient who had digestive symptoms was instructed as to how to control them.
Among PC patients, 50% were at risk of malnutrition compared to 7.5% in the BPH group, as assessed by the MNA questionnaire. Patients suffering from PC were more depressed than those with BPH. A higher degree of depressive symptomatology was related to poorer nutritional status. Assessment of nutritional status is important and should be routinely performed in older men with PC.
我们的目的是研究接受晚期前列腺癌（PC）治疗的老年男性的营养状况。
我们评估了80名患者：40名晚期PC患者（研究组）和40名良性前列腺增生（BPH）患者（对照组）。使用的工具包括：微型营养评定法（MNA）和耶萨维奇老年抑郁量表（GDS）简表。还询问了反映营养状况的补充问题。
PC患者的平均年龄为72（65 - 94）岁，对照组为71（65 - 85）岁。PC患者体重快速下降——15名（39.5%）患者在3个月内体重减轻超过3千克。抑郁症状在研究组中更为常见（p<0.05），且与营养状况呈负相关。年龄对抑郁症状无影响。消化系统疾病困扰着研究组中的23名（57.5%）患者和对照组中的14名（20%）患者。消化系统问题对两组患者的食欲均有影响，t = 0.54，r = 0.46（p<0.05）。没有向任何有消化系统症状的患者说明如何控制这些症状。
根据MNA问卷评估，PC患者中有50%存在营养不良风险，而BPH组为7.5%。PC患者比BPH患者更易抑郁。更高程度的抑郁症状与更差的营养状况相关。营养状况评估很重要，应该对老年PC男性患者进行常规评估。
