Ruppel Andreas, Chlichlia Katerina, Bahgat Mahmoud
Department of Tropical Hygiene and Public Health, University of Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.
Trends Parasitol. 2004 Sep;20(9):397-400. doi: 10.1016/j.pt.2004.06.006.
Skin invasion by schistosome cercariae was recently discussed in Trends in Parasitology. However, only Schistosoma mansoni was considered, possibly because this species predominates in laboratory studies (at least outside China). One may be tempted to extrapolate from the "model" S. mansoni to other schistosomes, but Schistosoma japonicum must not be neglected. This schistosome is distinguishable from others (particularly S. mansoni) by virtue of its remarkable speed and success of migration, as well as by specific biochemical and immunological features. This leads to the hypothesis that S. japonicum is atypical with respect to the enzymes that facilitate skin penetration.
最近《寄生虫学趋势》杂志讨论了血吸虫尾蚴对皮肤的侵袭。然而，仅考虑了曼氏血吸虫，这可能是因为该物种在实验室研究中占主导地位（至少在中国以外地区）。人们可能会试图从“模式”曼氏血吸虫推断到其他血吸虫，但日本血吸虫绝不能被忽视。这种血吸虫因其显著的迁移速度和成功率以及特定的生化和免疫学特征而与其他血吸虫（特别是曼氏血吸虫）有所区别。这就引出了一个假说，即日本血吸虫在促进皮肤穿透的酶方面是非典型的。
