Mazzone Luigi, Mugno Diego, Mazzone Domenico
Division of Child Neuropsychiatry, Department of Pediatrics, University of Catania, Via S. Sofia, 78, 95100 Catania, Italy.
Early Hum Dev. 2004 Sep;79(2):119-30. doi: 10.1016/j.earlhumdev.2004.04.013.
Aim of our study was to describe the character of General Movements (GMs) in children with Down Syndrome (DS).
GMs of 23 children with DS and of 30 healthy full-term infants were assessed from birth to 6th month corrected age. A qualitative and a semi-quantitative evaluation of GMs were achieved for each child. Data were graphically displayed to obtain growth curves of motor optimality scores.
GMs in children with DS are characterised by low-low/moderate speed, large-large/moderate amplitude, partially creating impression of fluency, smoothness and complexity, abrupt beginning and end, few other concurrent gross movements. During the 6 months, all children showed an improvement of qualitative and semi-quantitative evaluation, but it was possible to observe great heterogeneity among children in the evolutionary course. GMs evaluation of children with no known motor problems was normal, showing only slight and transient abnormalities at first months.
GMs character of children with DS could be related to central nervous system and peripheral abnormalities characterizing this syndrome. The evaluation of GMs in children with DS could be an early marker of motor impairment and help in early management decisions making.
我们研究的目的是描述唐氏综合征（DS）患儿的全身运动（GMs）特征。
对23名DS患儿和30名健康足月婴儿从出生至矫正年龄6个月进行GMs评估。对每个孩子的GMs进行了定性和半定量评估。数据以图形方式显示，以获得运动最优性评分的生长曲线。
DS患儿的GMs特征为低速/中速、大幅度/中等幅度，部分给人以流畅性、平滑性和复杂性的印象，起始和结束突然，很少有其他同时出现的大运动。在6个月期间，所有孩子的定性和半定量评估都有所改善，但在进化过程中可以观察到孩子之间存在很大的异质性。对没有已知运动问题的孩子进行的GMs评估是正常的，仅在最初几个月显示出轻微和短暂的异常。
DS患儿的GMs特征可能与该综合征所特有的中枢神经系统和周围异常有关。对DS患儿进行GMs评估可能是运动障碍的早期标志物，并有助于早期管理决策。
