Lau Mark A, Segal Zindel V, Williams J Mark G
Department of Psychiatry, Centre for Addiction and Mental Health, University of Toronto, 250 College Street, Ontario, Canada M5T 1R8.
Behav Res Ther. 2004 Sep;42(9):1001-17. doi: 10.1016/j.brat.2004.03.003.
Teasdale's differential activation hypothesis (DAH) has been proposed as one account of cognitive vulnerability to depression. This view holds that important factors determining whether one's initial depression becomes more severe or persistent are the degree of activation, and content, of negative thinking patterns that become accessible in the depressed state. This phenomenon has been referred to as cognitive reactivity. Empirical support for the predictions of this model derives from a combination of cross-sectional and prospective studies. In this article, we evaluate this evidence with the goal of determining whether mood-induced cognitive reactivity can be considered a risk factor for depressive relapse/recurrence. Our review demonstrates sufficient evidence to consider cognitive reactivity as a potential causal risk factor for depressive relapse/recurrence. Furthermore, we extend the application of this model to the problem of suicidal relapse/recurrence including a review of preliminary support for this approach.
蒂尔斯代尔的差异激活假说（DAH）已被提出，作为对抑郁症认知易感性的一种解释。这种观点认为，决定一个人最初的抑郁症是否会变得更严重或持续的重要因素是在抑郁状态下可及的消极思维模式的激活程度和内容。这种现象被称为认知反应性。对该模型预测的实证支持来自横断面研究和前瞻性研究的结合。在本文中，我们评估这一证据，目的是确定情绪诱发的认知反应性是否可被视为抑郁复发/再发的一个风险因素。我们的综述表明有足够的证据将认知反应性视为抑郁复发/再发的一个潜在因果风险因素。此外，我们将该模型的应用扩展到自杀复发/再发问题，包括对这种方法的初步支持的综述。
