Lane Margaret, McBride John, Archer John
Department of Infectious Diseases, Cairns Base Hospital, and School of Medicine, James Cook University, Queensland, Australia.
Neurology. 2004 Aug 24;63(4):713-4. doi: 10.1212/01.wnl.0000134677.29120.62.
The authors describe the clinical course of Cryptococcus neoformans variety gattii infection in a young immunocompetent man who had a late deterioration characterized by headaches, subarachnoid inflammation, hydrocephalus, and stroke that reproducibly responded to steroids. These findings, in combination with declining markers of CSF infection, are consistent with the late deterioration being caused by sterile arachnoiditis rather than ongoing infection.
作者描述了一名年轻免疫功能正常男性感染新型隐球菌格特变种的临床病程，该患者出现了以头痛、蛛网膜下腔炎症、脑积水和中风为特征的晚期病情恶化，而类固醇治疗对此有可重复性反应。这些发现，再加上脑脊液感染标志物的下降，表明晚期病情恶化是由无菌性蛛网膜炎而非持续性感染所致。
