Jungles Sandra L
Given Imaging, Inc., Norcross, Georgia, USA.
Gastroenterol Nurs. 2004 Jul-Aug;27(4):170-5. doi: 10.1097/00001610-200407000-00005.
Crohn's disease is a chronic immune-mediated disease that affects any or all segments of the gastrointestinal tract, but is mainly found in the small intestines or colon. Crohn's disease in the early stages present with symptoms such as chronic diarrhea, abdominal pain, and weight loss that may mimic other conditions and cause a delay in diagnosis. Many patients experience emotional difficulties related to this debilitating disease. Current procedures used to visualize the small bowel for diagnosis of Crohn's disease include small-bowel follow through, enteroclysis, and computerized tomography, but do not provide definition of the mucosal surface. Clinical research shows us the diagnostic yield of these tests are not as high as once thought. A new diagnostic tool, the M2A Video Capsule, can be used to visualize the small bowel mucosa. With the detailed photo images provided by the capsule, the physician now has the ability to detect subtle changes in the mucosal lining that may be consistent with early Crohn's disease that were previously not available or identifiable. Earlier disease treatment and management may decrease the inflammatory changes that lead to bowel thickening and stricturing and have a positive impact on the patient's total quality of life.
克罗恩病是一种慢性免疫介导性疾病，可累及胃肠道的任何部分或全部，但主要见于小肠或结肠。早期克罗恩病的症状包括慢性腹泻、腹痛和体重减轻，这些症状可能与其他疾病相似，导致诊断延迟。许多患者会因这种使人衰弱的疾病而出现情绪问题。目前用于诊断克罗恩病的小肠可视化检查方法包括小肠钡剂造影、小肠灌肠造影和计算机断层扫描，但这些方法无法清晰显示黏膜表面。临床研究表明，这些检查的诊断率并不像人们曾经认为的那么高。一种新的诊断工具——M2A视频胶囊，可用于可视化小肠黏膜。借助该胶囊提供的详细照片图像，医生现在能够检测到黏膜内层的细微变化，这些变化可能与早期克罗恩病相符，而这些变化在以前是无法获得或识别的。早期的疾病治疗和管理可能会减少导致肠壁增厚和狭窄的炎症变化，并对患者的整体生活质量产生积极影响。
