Kronberger Irmgard E, Graziadei Ivo W, Vogel Wolfgang
Department of Gastroenterology and Hepatology, Anichstrasse 35, A-6020 Innsbruck, Austria.
World J Gastroenterol. 2006 Feb 28;12(8):1317-20. doi: 10.3748/wjg.v12.i8.1317.
Small bowel adenocarcinomas are remarkable for their rarity, difficult diagnosis and poor prognosis. Here we report an unusual case of a 33-year-old patient in whom infiltrative adenocarcinoma of the small bowel was diagnosed after a 10-year history of Crohn's disease. In most previously reported cases, detection of Crohn's disease was subsequent to that of carcinoma of the small bowel or the patients involved had an even longer history of the disease. Our literature review suggests that the risk of small bowel adenocarcinoma is higher in patients with Crohn's disease than in the overall population. We present details on epidemiology as well as clinical and diagnostic aspects of this rare disease entity.
小肠腺癌因其罕见、诊断困难和预后不良而引人注目。在此，我们报告一例不寻常的病例，一名33岁患者，在患有克罗恩病10年后被诊断为小肠浸润性腺癌。在大多数先前报道的病例中，克罗恩病是在小肠癌被发现之后才被检测到，或者所涉及的患者患有该病的病史更长。我们的文献综述表明，克罗恩病患者患小肠腺癌的风险高于普通人群。我们介绍了这种罕见疾病实体的流行病学以及临床和诊断方面的详细情况。
