Stav Kobi, Leibovici Dan, Goren Elyahu, Livshitz Anna, Siegel Yoram I, Lindner Arie, Zisman Amnon
Department of Urology, Assaf Harofeh Medical Center, Zerifin, Israel.
Isr Med Assoc J. 2004 Aug;6(8):474-8.
Cystoscopy, the principal means of diagnosis and surveillance of bladder tumors, is invasive and associated with unpleasant side effects.
To determine the early complications of rigid cystoscopy and the impact on patients' quality of life and sexual performance.
One hundred consecutive patients undergoing diagnostic rigid cystoscopy filled in questionnaires that included anxiety and pain levels (0-5 visual analogue scale), adverse events, Short-Form Health Survey, International Prostate Symptom Score, and functional sexual performance. Questionnaires were administered before, immediately after, and 1, 2 days, 2 and 4 weeks following cystoscopy.
The pre-cystoscopy anxiety level was 2.01. The average pain during the examination was 1.41. SF-36 score was not affected by cystoscopy. The subjective impact on patients' quality of life was 0.51. The mean IPSS increased following cystoscopy (6.75 vs. 5.43, P = 0.001) and returned to baseline 2 weeks later. A decline in libido was reported by 55.6% (25/45) and 50% (3/6) of the sexually active men and women, respectively. Cystoscopy was associated with a decreased Erectile Dysfunction Intensity Score, from 15.6 to 9.26 during the first 2 weeks (P = 0.04). The overall complication rate was 15% and included urethrorrhagia and dysuria, None of the patients had fever or urinary retention and none was hospitalized. The complication rate was higher in patients with benign prostatic hyperplasia (24% vs. 9.7%, P = 0.001).
Rigid cystoscopy is well tolerated by most patients and has only a minor impact on quality of life. However, cystoscopy transiently impairs sexual performance and libido. The early complications are mild and correlate with a diagnosis of BPH.
膀胱镜检查是诊断和监测膀胱肿瘤的主要手段,具有侵入性且伴有不适的副作用。
确定硬性膀胱镜检查的早期并发症及其对患者生活质量和性功能的影响。
100例连续接受诊断性硬性膀胱镜检查的患者填写问卷,内容包括焦虑和疼痛程度(0 - 5视觉模拟评分)、不良事件、简短健康调查问卷、国际前列腺症状评分以及性功能。问卷在膀胱镜检查前、检查后即刻、检查后1天、2天、2周和4周进行发放。
膀胱镜检查前焦虑水平为2.01。检查期间平均疼痛程度为1.41。简短健康调查问卷(SF - 36)评分不受膀胱镜检查影响。对患者生活质量的主观影响评分为0.51。膀胱镜检查后国际前列腺症状评分均值升高(6.75对5.43,P = 0.001),2周后恢复至基线水平。分别有55.6%(25/45)的性活跃男性和50%(3/6)的性活跃女性报告性欲下降。膀胱镜检查与勃起功能障碍强度评分降低相关,在最初2周内从15.6降至9.26(P = 0.04)。总体并发症发生率为15%,包括尿道出血和排尿困难,无患者发热或尿潴留,也无患者住院。良性前列腺增生患者并发症发生率更高(24%对9.7%,P = 0.001)。
大多数患者对硬性膀胱镜检查耐受性良好,对生活质量影响较小。然而,膀胱镜检查会暂时损害性功能和性欲。早期并发症较轻,且与良性前列腺增生的诊断相关。