Boyd James C
Department of Pathology, University of Virginia Health System, Charlottesville, 22901, USA.
Clin Chem Lab Med. 2004;42(7):739-46. doi: 10.1515/CCLM.2004.125.
Despite being proposed over 30 years ago, the multivariate reference region (MRR) remains an interpretive tool with uncertain value in clinical practice. This paper reviews the mathematical theory of the MRR, presents topics in the clinical application of MRRs, and examines the advantages and disadvantages of MRRs. Finally, some thoughts are offered regarding future directions for work in this field.
尽管多元参考区域(MRR)在30多年前就已被提出,但它在临床实践中仍然是一种价值不确定的解释工具。本文回顾了MRR的数学理论,介绍了MRR在临床应用中的主题,并探讨了MRR的优缺点。最后,针对该领域未来的工作方向提出了一些想法。