Pisters K M, Kris M G
Division of Solid Tumor Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY.
Oncology (Williston Park). 1992 Feb;6(2 Suppl):99-104.
Our understanding and management of chemotherapy-induced nausea and vomiting has progressed substantially in the past decade. We now have many effective single agents, which are even more beneficial when used in appropriate combinations. A new class of antiemetic agents, the serotonin antagonists, of which ondansetron is the first to be commercially available, promises significantly better control of the various emetic syndromes caused by cancer chemotherapy, with fewer side effects. This article summarizes the state of the art of antiemetic therapy.
在过去十年中，我们对化疗引起的恶心和呕吐的理解及管理取得了显著进展。我们现在有许多有效的单一药物，当以适当的组合使用时，它们会更有益。一类新的止吐药，即血清素拮抗剂，其中昂丹司琼是首个上市的药物，有望能显著更好地控制由癌症化疗引起的各种呕吐综合征，且副作用更少。本文总结了止吐治疗的最新进展。
