Reimann F, Celik E
Rofo. 1978 Dec;129(6):762-5. doi: 10.1055/s-0029-1231201.
Lateral X-ray pictures of the skull in certain several and chronic disorders of the blood as thalassaemia, congenital haemolytic anaemia, sickle cell anaemia and iron deficiency disease show frequently changes of the outlines of the cranial bones. They consist of a double contour of the outer cranial border and on the interior side below the sagittal sutura of a band-like shadow or of multiple stripes and lines running parallel to the carnial vault. They concern the parietal bones and may extend from the bregma till to the lamda or occupy only a part of this distance. The roentgenological features are due to the enlargement of the crainal bones, the bulging out of both parietal bondes, the sometimes enlarged and deepened borders of the sulcus sagittalis superior and particularly to the furrow and depression on the skull above the sagittal suture caused by the protruding parietal bones on both sides. As these different abnormal structures must be passed by the picturing X-ray, effects of superposition and interference are produced. Longitudinal ridges or bony edges which could explain the roentgenological findings could not be established. Since the peculiar alterations of the cranial bones are mainly found in the mentioned blood disorders, where they are caused by the overgrowing red marrow, they also display the same roentgenological features. These features are, therefore, a characteristic sign of these diseases.
在某些几种慢性血液疾病如地中海贫血、先天性溶血性贫血、镰状细胞贫血和缺铁性疾病中，颅骨的侧位X线片经常显示颅骨轮廓的改变。它们表现为颅外边界的双重轮廓，在矢状缝下方内侧有一条带状阴影或多条与颅顶平行的条纹和线。它们涉及顶骨，可从囟门延伸至枕外隆凸，或仅占据这段距离的一部分。这些X线特征是由于颅骨增大、双侧顶骨膨出、有时上矢状沟边界增大和加深，特别是由于双侧顶骨突出导致矢状缝上方颅骨出现沟和凹陷。由于这些不同的异常结构必须被成像X线穿过，所以会产生叠加和干扰效应。无法确定能解释这些X线表现的纵向嵴或骨边缘。由于颅骨的特殊改变主要见于上述血液疾病中，是由过度生长的红骨髓引起的，所以它们也表现出相同的X线特征。因此，这些特征是这些疾病的特征性标志。
