Maejima Yasuhiro, Yasu Takanori, Kubo Norifumi, Kawahito Koji, Omura Nobuhiro, Katsuki Takaaki, Tsukamoto Yoshiaki, Sugawara Yoshitaka, Hashimoto Shigemasa, Tsuruya Yoshio, Hirahara Taishi, Takagi Yosuke, Kobayashi Nobuhiko, Funayama Hiroshi, Ikeda Nahoko, Ishida Takeshi, Fujii Mikihisa, Ino Takashi, Saito Muneyasu
The Division of Cardiovascular Surgery, Omiya Medical Center, Jichi Medical School, Amanuma, Omiya, Japan.
Circ J. 2004 Sep;68(9):829-33. doi: 10.1253/circj.68.829.
The long-term prognosis and cardiac function of fulminant myocarditis treated with percutaneous cardiopulmonary support (PCPS) was compared with the outcome of those not treated with PCPS.
From 1991 to 2000, 14 patients with fulminant myocarditis (left ventricle ejection fraction (LVEF) < or =40%) were admitted to hospital. PCPS was necessary for treatment of shock in 8 (PCPS group), but not for the remaining 6 patients (non-PCPS group). In the PCPS group, 6 patients (75%) survived the critical phase and did not have any cardiac problems after discharge (range of follow-up period, 1.4-6.0 years). All patients in the non-PCPS group survived the acute phase; 1 patient had congestive heart failure 1.5 years after discharge, and another died from malignancy (follow-up period range, 2.2-9.4 years). Although the left ventricular ejection fraction (LVEF) of the PCPS group was significantly lower than that of the non-PCPS group in the acute phase, there was no significant difference in LVEF between the 2 groups in the chronic phase.
Patients who survive the acute phase crisis of acute myocarditis have a favorable long-term survival rate, whether or not mechanical support is used.
比较经皮心肺支持（PCPS）治疗暴发性心肌炎的长期预后和心功能与未接受PCPS治疗的患者的结局。
1991年至2000年，14例暴发性心肌炎患者（左心室射血分数[LVEF]≤40%）入院。8例患者（PCPS组）治疗休克需要PCPS，其余6例患者（非PCPS组）不需要。在PCPS组，6例患者（75%）度过危险期存活，出院后无任何心脏问题（随访期1.4 - 6.0年）。非PCPS组所有患者急性期存活；1例患者出院1.5年后出现充血性心力衰竭，另1例死于恶性肿瘤（随访期2.2 - 9.4年）。虽然急性期PCPS组的左心室射血分数（LVEF）显著低于非PCPS组，但慢性期两组之间LVEF无显著差异。
急性心肌炎急性期危机存活的患者，无论是否使用机械支持，长期生存率都较好。
