Kuji I, Nakajima K, Taki J, Taniguchi M, Bunko H, Tonami N, Hisada K
Department of Nuclear Medicine, Kanazawa University School of Medicine.
Kaku Igaku. 1992 Feb;29(2):183-91.
Characteristics of the myocardial distribution of 99mTc-MIBI and 99mTc-Teboroxime was compared with the myocardial distribution of 201Tl. We made summed myocardial images, in which central three short-axis SPECT slices were added. Rectangular region of interest (ROI) was set on each myocardial segment, and mean counts of each myocardial region was obtained using summed short-axis images. The ratio of inferior-to-anterior mean counts (I/A) was 0.69 +/- 0.20 in 99mTc-MIBI and 0.62 +/- 0.16 in 201Tl. The ratio of inferior-to-lateral mean counts was 0.70 +/- 0.18 and 0.65 +/- 0.13, respectively. Both ratios in 99mTc-MIBI were significantly higher than those in 201Tl (p less than 0.05). 201Tl to 99mTc-MIBI ratios of these two values were 1.11 +/- 0.17 (I/A) and 1.08 +/- 0.16 (I/L). The ratios of I/A and I/L of 99mTc-MIBI were about 10 percent higher than those of 201Tl. 99mTc-Teboroxime dynamic short-axis SPECT images of every three-minute were obtained. The ratios of counts in each wall were calculated similarly. After about 8 minutes, gradual increase in hepatic activity can be a cause of quantitative error in the assessment of SPECT images. We obtained the data with a human cardiac phantom. The myocardial phantom filled with 99mTc or 201Tl was placed in the mediastinal portion that is surrounded by the lung (saw dust) and vertebra (plastic bar). The ratio of I/A was 0.79 and I/L was 0.85 in 201Tl. The I/A ratio was 0.93 and I/L was 0.97 in 99mTc. Both ratios in 99mTc were about 15 percent higher than those in 201Tl.(ABSTRACT TRUNCATED AT 250 WORDS)
将99mTc - MIBI和99mTc - Teboroxime的心肌分布特征与201Tl的心肌分布进行了比较。我们制作了总和心肌图像，其中添加了中央三个短轴SPECT切片。在每个心肌节段上设置矩形感兴趣区（ROI），并使用总和短轴图像获得每个心肌区域的平均计数。99mTc - MIBI下壁与前壁平均计数之比（I/A）为0.69±0.20，201Tl为0.62±0.16。下壁与侧壁平均计数之比分别为0.70±0.18和0.65±0.13。99mTc - MIBI的这两个比值均显著高于201Tl（p＜0.05）。这两个值的201Tl与99mTc - MIBI比值分别为1.11±0.17（I/A）和1.08±0.16（I/L）。99mTc - MIBI的I/A和I/L比值比201Tl高约10%。获得了每三分钟的99mTc - Teboroxime动态短轴SPECT图像。以类似方式计算各壁的计数比值。约8分钟后，肝脏活性的逐渐增加可能导致SPECT图像评估中的定量误差。我们使用人体心脏模型获得了数据。将填充有99mTc或201Tl的心肌模型置于由肺（锯末）和椎骨（塑料棒）包围的纵隔部分。201Tl的I/A比值为0.79，I/L为0.85。99mTc的I/A比值为0.93，I/L为0.97。99mTc的这两个比值均比201Tl高约15%。（摘要截取自250字）
