Dergacheva O Yu, Khachikova I E, Burikov A A
A. B. Kogan Science Research Institute of Neurocybernetics, Rostov State University, 194/1 Stachka Prospekt, 344090 Rostov-on-Don, Russia.
Neurosci Behav Physiol. 2004 Jun;34(5):485-9. doi: 10.1023/b:neab.0000022634.17261.aa.
Chronic experiments on five cats were performed to study the spike activity of neurons in the oral nucleus of the pons during waking, slow-wave sleep, and paradoxical sleep. Groups of neurons with different dynamics of spike frequency were identified. Cells with rare discharges during waking and slow-wave sleep and maximum spike frequencies in the phasic stage of paradoxical sleep were regarded as PS-on neurons. Cells discharging at maximum frequency during waking, with decreases in frequency during slow-wave sleep and further decreases in paradoxical sleep, were regarded as PS-off neurons. Cells showing decreases in discharge frequency on the transition from waking to slow-wave sleep and increases in discharge frequency in paradoxical sleep, with grouped spikes during oculomotor activity, appeared to be responsible for generating the phasic phenomena of paradoxical sleep. The question of the involvement of neurons of different populations in the mechanisms of paradoxical sleep is discussed.
对五只猫进行了慢性实验，以研究脑桥口核神经元在清醒、慢波睡眠和异相睡眠期间的锋电位活动。识别出了具有不同锋电位频率动态的神经元群。在清醒和慢波睡眠期间放电稀少、在异相睡眠的相位期具有最大锋电位频率的细胞被视为PS-on神经元。在清醒期间以最大频率放电、在慢波睡眠期间频率降低且在异相睡眠期间进一步降低的细胞被视为PS-off神经元。在从清醒过渡到慢波睡眠时放电频率降低、在异相睡眠时放电频率增加且在动眼活动时有成簇锋电位的细胞似乎负责产生异相睡眠的相位现象。讨论了不同群体的神经元参与异相睡眠机制的问题。
