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从小石块上跳下并伴有打喷嚏发作后发生的鼻窦血栓形成:轻微内皮损伤作为脑静脉血栓形成的诱发因素?

Sinus thrombosis after a jump from a small rock and a sneezing attack: minor endothelial trauma as a precipitating factor for cerebral venous thrombosis?

作者信息

Röttger Carina, Trittmacher Susan, Gerriets Tibo, Kaps Manfred, Stolz Erwin

机构信息

Department of Neurology, University of Giessen, Germany.

出版信息

Headache. 2004 Sep;44(8):812-5. doi: 10.1111/j.1526-4610.2004.04150.x.

Abstract

Cerebral venous thrombosis (CVT) associated with minor or trivial head trauma has only been described in a few cases so far. We report two patients who developed CVT after a sudden intracranial pressure increase and head acceleration. A 49-year-old woman jumped from a small rock, 1 m in height, and developed instantaneous occipital headaches. Magnetic resonance imaging (MRI) confirmed confluens sinuum thrombosis. Risk factors consisted of smoking and oral contraceptives. Our second patient, an 18-year-old woman, experienced instantaneous headaches after a sneezing attack. Superior sagittal and right-sided transverse sinus thrombosis were confirmed by venous computed tomography angiography. She took oral contraceptives as an additional risk factor. In about 20% of CVT cases the cause remains unclear. As minor head trauma may not have been recognized during history taking, this may represent a so far under-recognized precipitating factor for CVT.

摘要

迄今为止,仅有少数病例报道过与轻微头部外伤相关的脑静脉血栓形成(CVT)。我们报告了两名患者,他们在颅内压突然升高和头部加速后发生了CVT。一名49岁女性从1米高的小岩石上跳下,随即出现枕部头痛。磁共振成像(MRI)证实为窦汇血栓形成。危险因素包括吸烟和口服避孕药。我们的第二名患者是一名18岁女性,在打喷嚏发作后立即出现头痛。静脉计算机断层血管造影证实为上矢状窦和右侧横窦血栓形成。她服用口服避孕药,这是另外一个危险因素。在约20%的CVT病例中,病因仍不清楚。由于在病史采集过程中可能未识别出轻微头部外伤,这可能是迄今为止CVT一个未被充分认识的诱发因素。

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