Berk M, Malhi G S, Mitchell P B, Cahill C M, Carman A C, Hadzi-Pavlovic D, Hawkins M T, Tohen M
Barwon Health and The Geelong Clinic, Geelong, Australia.
Acta Psychiatr Scand Suppl. 2004(422):39-45. doi: 10.1111/j.1600-0447.2004.00412.x.
To briefly review the clinical and biological distinctions between unipolar and bipolar depression critiquing in particular currently available depression rating scales and discuss the need for a new observer-rated scale tailored to bipolar depression.
Relevant literature pertaining to the symptomatic differences between bipolar disorder and unipolar disorder as well as their measurement using existing assessment scales was identified by computerized searches and reviews of scientific journals known to the authors.
Bipolar depression is distinct from unipolar depression in terms of phenomenology and clinical characteristics. These distinguishing features can be used to identify bipolarity in patients that present with recurrent depressive episodes. This is important because current self-report and observer-rated scales are optimized for unipolar depression, and hence limited in their ability to accurately assess bipolar depression.
The development of a specific bipolar depression rating scale will improve the assessment of bipolar depression in both research and clinical settings and assist the development of better treatments and interventions.
简要回顾单相抑郁和双相抑郁之间的临床及生物学差异，尤其对目前可用的抑郁评定量表进行批判，并讨论开发一种专门针对双相抑郁的新的观察者评定量表的必要性。
通过计算机检索以及作者所知科学期刊的综述，确定了与双相情感障碍和单相情感障碍之间的症状差异以及使用现有评估量表对其进行测量相关的文献。
双相抑郁在现象学和临床特征方面与单相抑郁不同。这些区别特征可用于识别出现复发性抑郁发作的患者的双相性。这很重要，因为目前的自我报告和观察者评定量表是针对单相抑郁进行优化的，因此在准确评估双相抑郁方面能力有限。
开发一种特定的双相抑郁评定量表将改善研究和临床环境中对双相抑郁的评估，并有助于开发更好的治疗方法和干预措施。
