重氮氮霉素，一种来自海洋小单孢菌属的新型抗菌生物碱。

Diazepinomicin, a new antimicrobial alkaloid from a marine Micromonospora sp.

作者信息

Charan Romila D, Schlingmann Gerhard, Janso Jeffrey, Bernan Valerie, Feng Xidong, Carter Guy T

机构信息

Chemical and Screening Sciences, Wyeth Research, 401 N. Middletown Road, Pearl River, New York 10965, USA.

出版信息

J Nat Prod. 2004 Aug;67(8):1431-3. doi: 10.1021/np040042r.

DOI:10.1021/np040042r

PMID:15332871

Abstract

The structure of a new dibenzodiazepine alkaloid, diazepinomicin (1), isolated from the culture of a marine actinomycete of the genus Micromonospora was characterized using spectroscopic methods. Diazepinomicin represents a unique molecular class composed of a dibenzodiazepine core linked to a farnesyl side chain.

摘要

从微小单孢菌属海洋放线菌培养物中分离出的一种新型二苯并二氮杂卓生物碱——重氮氮霉素（1）的结构，通过光谱方法进行了表征。重氮氮霉素代表了一类独特的分子，由与法尼基侧链相连的二苯并二氮杂卓核心组成。