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孤立性肋骨骨转移揭示的消退型精原细胞瘤

Burned-out seminoma revealed by solitary rib bone metastasis.

作者信息

Nishisho Toshihiko, Sakaki Mika, Miyagi Ryo, Takao Shoichiro, Sairyo Koichi

机构信息

Department of Orthopedics, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15 Kuramoto-cho, Tokushima-city, 770-8503, Tokushima, Japan.

Department of Pathology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka-city, 350-1298, Saitama, Japan.

出版信息

Skeletal Radiol. 2017 Oct;46(10):1415-1420. doi: 10.1007/s00256-017-2701-y. Epub 2017 Jun 21.

Abstract

Burned-out tumor is a rare phenomenon in which a testicular tumor regresses in the primary lesion and progresses in a metastatic lesion. We report the case of a 30-year-old male with burned-out seminoma revealed by open biopsy of solitary 10th rib bone metastasis. He underwent inguinal orchiectomy, which revealed hyalinization, indicating a spontaneously regressed testicular tumor. Chemotherapy for seminoma was administered in three cycles of bleomycin + etoposide + cisplatin therapy. The chemotherapy was effective, and wide resection of the rib was subsequently performed. No postoperative chemotherapy was performed, and there has been no evidence of recurrence for 3 years postoperatively.

摘要

肿瘤自行消退是一种罕见现象,即睾丸肿瘤在原发灶消退而在转移灶进展。我们报告一例30岁男性,因孤立的第10肋骨转移灶开放活检发现自行消退的精原细胞瘤。他接受了腹股沟睾丸切除术,术中发现透明变性,提示睾丸肿瘤自发消退。采用博来霉素+依托泊苷+顺铂方案进行了三个周期的精原细胞瘤化疗。化疗有效,随后对肋骨进行了广泛切除。术后未进行化疗,术后3年无复发迹象。

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