Nishisho Toshihiko, Sakaki Mika, Miyagi Ryo, Takao Shoichiro, Sairyo Koichi
Department of Orthopedics, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15 Kuramoto-cho, Tokushima-city, 770-8503, Tokushima, Japan.
Department of Pathology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka-city, 350-1298, Saitama, Japan.
Skeletal Radiol. 2017 Oct;46(10):1415-1420. doi: 10.1007/s00256-017-2701-y. Epub 2017 Jun 21.
Burned-out tumor is a rare phenomenon in which a testicular tumor regresses in the primary lesion and progresses in a metastatic lesion. We report the case of a 30-year-old male with burned-out seminoma revealed by open biopsy of solitary 10th rib bone metastasis. He underwent inguinal orchiectomy, which revealed hyalinization, indicating a spontaneously regressed testicular tumor. Chemotherapy for seminoma was administered in three cycles of bleomycin + etoposide + cisplatin therapy. The chemotherapy was effective, and wide resection of the rib was subsequently performed. No postoperative chemotherapy was performed, and there has been no evidence of recurrence for 3 years postoperatively.
肿瘤自行消退是一种罕见现象,即睾丸肿瘤在原发灶消退而在转移灶进展。我们报告一例30岁男性,因孤立的第10肋骨转移灶开放活检发现自行消退的精原细胞瘤。他接受了腹股沟睾丸切除术,术中发现透明变性,提示睾丸肿瘤自发消退。采用博来霉素+依托泊苷+顺铂方案进行了三个周期的精原细胞瘤化疗。化疗有效,随后对肋骨进行了广泛切除。术后未进行化疗,术后3年无复发迹象。