Dugas B, Mencia-Huerta J M, Braquet P
Département d'Immunologie, Institut Henri Beaufour, Les Ulis, France.
Eur Cytokine Netw. 1992 Jan-Feb;3(1):35-41.
This review relates the molecular and the functional aspects of the low affinity IgE receptor for IgE (CD23), and the possible cooperation with additional cytokines, lipid mediators and/or pharmacological agents (i.e. beta 2-adrenoceptor agonists etc ...) that appear to be involved in the regulation of the IgE-dependent immune and inflammatory responses in human. The possible contribution of CD23 to the initiation and the development of various diseases is also discussed.
本综述阐述了IgE低亲和力受体(CD23)的分子及功能方面,以及其与其他细胞因子、脂质介质和/或药物制剂(如β2 -肾上腺素能受体激动剂等)可能存在的协同作用,这些细胞因子、脂质介质和药物制剂似乎参与了人类IgE依赖性免疫和炎症反应的调节。同时也讨论了CD23在各种疾病发生和发展过程中可能发挥的作用。