Mastrolonardo Mario, Diaferio Annalisa, Vendemiale Gianluigi, Lopalco Pierluigi
Department of Dermatology, University of Foggia, Bari, Italy.
Acta Derm Venereol. 2004;84(4):285-7. doi: 10.1080/00015550410025877.
The constant increase of life expectancy in countries with high standards of living raises growing concern about many aspects of skin morbidity in the elderly. As regards seborrhoeic dermatitis, literature yields prevalence estimates for elderly people that are consistently higher than those reported from the general population. This prompts speculations on whether factors inherently involved in senescence might have some role in the course of seborrhoeic dermatitis. In a series of 186 subjects, aged > or =65, strength of association of the skin disorder with age, sex, coexisting non-cutaneous conditions, and degree of loss of self-sufficiency in activities of daily living (ADL index) was evaluated by univariate and multivariate analysis. We found that age (OR: 1.14; p<0.001) and, more importantly, dependency in more than one ADL (OR: 30.2; p<0.0001) were independent explanatory variables of seborrhoeic dermatitis. These findings suggest that senescence per se might have some significance in the natural history of this type of eczema.
在生活水平较高的国家,人均寿命的不断增长引发了人们对老年人皮肤疾病诸多方面的日益关注。就脂溢性皮炎而言,文献显示老年人的患病率估计始终高于普通人群。这引发了人们对于衰老过程中内在因素是否在脂溢性皮炎病程中发挥作用的猜测。在一组186名年龄≥65岁的受试者中,通过单因素和多因素分析评估了该皮肤疾病与年龄、性别、并存的非皮肤疾病以及日常生活活动自理能力丧失程度(ADL指数)之间的关联强度。我们发现年龄(比值比:1.14;p<0.001),更重要的是,一项以上日常生活活动存在依赖(比值比:30.2;p<0.0001)是脂溢性皮炎的独立解释变量。这些发现表明衰老本身可能在这类湿疹的自然病程中具有一定意义。