Huang Zirui, Lin Jiahua, Ding Qike, Li Xiaoting, Lin Lihong, Lu Tao
Department of Dermatology, First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.
Arch Dermatol Res. 2025 Feb 8;317(1):381. doi: 10.1007/s00403-025-03870-3.
Seborrheic dermatitis (SD), an inflammatory dermatosis, significantly lowers quality of life, particularly in the elderly. Although studies have focused on the burden of SD globally before, trends among people 55 and older have received less attention. Utilizing the data released in 2021 by the Global Burden of Disease (GBD) consortium, our research was conducted to evaluate the global, regional, and national burden of SD in adults over 55 between 1990 and 2021 through incidence, prevalence, and disability-adjusted life years (DALYs) alongside advanced methods such as joinpoint regression analysis. We also performed decomposition analysis to examine the contributions of population and epidemiological changes. Correlation analysis was used to explore the assocaition between Socio-demographic Index (SDI) /climate-related parameters and SD. The global incidence of SD among adults aged 55 and older markedly rose from 1990 to 2021. The incidence grew by 120.84%, the prevalence by 125.09%, and the DALYs rose by 124.25%. Higher burdens were observed in the high and high-middle SDI regions, whereas low SDI areas displayed the highest age-standardized rates. Environmental factors, particularly global warming, were strongly connected with the incidence and prevalence of SD. Future projections suggested continued increases in SD cases through 2040. This study highlights the increasing burden of SD among older adults, emphasizing the role of demographic and environmental factors. Targeted public health interventions addressing aging populations and climate-related risks are urgent to mitigate the impact of SD globally.
脂溢性皮炎(SD)是一种炎症性皮肤病,会显著降低生活质量,在老年人中尤为如此。尽管此前已有研究关注全球范围内脂溢性皮炎的负担,但对55岁及以上人群的趋势关注较少。利用全球疾病负担(GBD)研究小组2021年发布的数据,我们开展了此项研究,通过发病率、患病率和伤残调整生命年(DALY),并运用连接点回归分析等先进方法,评估1990年至2021年间55岁以上成年人脂溢性皮炎的全球、区域和国家负担。我们还进行了分解分析,以检验人口和流行病学变化的贡献。采用相关分析来探究社会人口指数(SDI)/气候相关参数与脂溢性皮炎之间的关联。1990年至2021年间,55岁及以上成年人脂溢性皮炎的全球发病率显著上升。发病率增长了120.84%,患病率增长了125.09%,伤残调整生命年增长了124.25%。在高社会人口指数地区和高中等社会人口指数地区观察到更高的负担,而低社会人口指数地区的年龄标准化发病率最高。环境因素,尤其是全球变暖,与脂溢性皮炎的发病率和患病率密切相关。未来预测表明,到2040年脂溢性皮炎病例数将持续增加。这项研究凸显了老年人脂溢性皮炎负担的增加,强调了人口和环境因素的作用。针对老龄化人口和气候相关风险的有针对性的公共卫生干预措施对于减轻全球脂溢性皮炎的影响至关重要。