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犬鼓泡灌洗及长期抗菌药物治疗后中耳炎的疗效评估:44例(1998 - 2002年)

Evaluation of outcome of otitis media after lavage of the tympanic bulla and long-term antimicrobial drug treatment in dogs: 44 cases (1998-2002).

作者信息

Palmeiro Brian S, Morris Daniel O, Wiemelt Staci P, Shofer Frances S

机构信息

Department of Clinical Studies, School of Veterinary, Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

出版信息

J Am Vet Med Assoc. 2004 Aug 15;225(4):548-53. doi: 10.2460/javma.2004.225.548.

Abstract

OBJECTIVE

To evaluate the outcome of otitis media in dogs after video-otoscopic lavage of the tympanic bulla and long-term antimicrobial drug treatment.

DESIGN

Retrospective study.

ANIMALS

44 dogs with otitis media treated in an academic referral practice.

PROCEDURE

Medical records were reviewed for signalment, duration of ear canal disease, previous medical treatments, dermatologic diagnosis, results of cytologic examination and microbial culture of ear canal exudate, findings during video-otoscopy, medical treatment, days to resolution, and maintenance treatments prescribed. Four independent variables (age, duration of ear canal disease prior to referral, use of corticosteroids in treatment regimens, and infection with Pseudomonas aeruginosa) were evaluated statistically for potential influence on time to resolution.

RESULTS

Mean +/- SD (range) duration of ear canal disease prior to referral was 24.9 +/- 21.6 (3 to 84) months. Otitis media in 36 dogs resolved after lavage of the tympanic bulla and medical management; mean +/- SD (range) time to resolution was 117 +/- 86.7 (30 to 360) days. Time to resolution was not significantly influenced by any variable evaluated. Three dogs were lost to follow-up, and 4 dogs eventually required surgical intervention. Seven of 36 dogs in which otitis had resolved relapsed; 4 required additional lavage procedures.

CONCLUSIONS AND CLINICAL RELEVANCE

Results indicate that lavage of the tympanic bulla combined with medical management is an effective and viable option for treatment of otitis media in dogs.

摘要

目的

评估犬鼓室冲洗及长期抗菌药物治疗后中耳炎的治疗效果。

设计

回顾性研究。

动物

44只在学术转诊机构接受治疗的患中耳炎的犬。

方法

查阅病历,记录动物特征、耳道疾病持续时间、既往治疗情况、皮肤病诊断结果、耳道渗出液的细胞学检查和微生物培养结果、耳内镜检查结果、治疗方法、治愈天数及所开的维持治疗方案。对四个独立变量(年龄、转诊前耳道疾病持续时间、治疗方案中是否使用皮质类固醇以及是否感染铜绿假单胞菌)进行统计学评估,以确定其对治愈时间的潜在影响。

结果

转诊前耳道疾病的平均±标准差(范围)持续时间为24.9±21.6(3至84)个月。36只犬的中耳炎在鼓室冲洗及药物治疗后治愈;平均±标准差(范围)治愈时间为117±86.7(30至360)天。所评估的任何变量均未对治愈时间产生显著影响。3只犬失访,4只犬最终需要手术干预。36只治愈犬中有7只复发;4只需要再次进行冲洗治疗。

结论及临床意义

结果表明,鼓室冲洗联合药物治疗是治疗犬中耳炎的一种有效且可行的选择。

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