Leone Marc, Garnier Franck, Avidan Michael, Martin Claude
Department of Anesthesiology and Intensive Care Medicine, CHU Nord, AP-HM, Marseilles Hospital University System, Chemin des Bourrelys, 13915 Marseille cedex 20, France.
Microbes Infect. 2004 Sep;6(11):1026-32. doi: 10.1016/j.micinf.2004.05.016.
The purpose of this review is to analyze literature concerning the diagnosis, prevention, and management of catheter-associated urinary tract infection (CAUTI) occurring in patients hospitalized in the intensive care unit (ICU). Analysis was performed from personal and "Pubmed" data, crossing the following keywords: "urinary tract infection", "catheter', and "intensive care unit". Few clinical trials including ICU patients were found despite the abundance of expert opinions. There is no consensus on the use of urinary reagent tests for diagnosis. The prevention of CAUTI in ICU patients does not require expensive devices. Neither complex closed drainage systems nor silver-coated urinary catheters have demonstrated efficacy in comparative randomized clinical trials. Bladder irrigation should not be used, except when an obstruction of the catheter is highly likely. The administration of prophylactic antimicrobial therapy, although effective in reducing the incidence of urinary bacteria, cannot be recommended in ICU patients. The management of CAUTI in ICU patients has not been evaluated in clinical trials. The level of evidence provided in this field is weak, and underlines the need for randomized studies to improve management of patients.
本综述的目的是分析有关重症监护病房(ICU)住院患者发生的导管相关尿路感染(CAUTI)的诊断、预防和管理的文献。分析是根据个人资料和“PubMed”数据进行的,交叉使用了以下关键词:“尿路感染”、“导管”和“重症监护病房”。尽管有大量专家意见,但发现涉及ICU患者的临床试验很少。对于使用尿液试剂检测进行诊断尚无共识。ICU患者CAUTI的预防不需要昂贵的设备。在比较随机临床试验中,复杂的封闭式引流系统和镀银导尿管均未显示出有效性。除非极有可能出现导管阻塞,否则不应使用膀胱冲洗。预防性抗菌治疗虽能有效降低尿路细菌感染率,但不建议在ICU患者中使用。ICU患者CAUTI的管理尚未在临床试验中进行评估。该领域提供的证据水平较弱,强调需要进行随机研究以改善患者管理。