Sibenge S, Gawkrodger D J
Department of Dermatology, University of Sheffield, Royal Hallamshire Hospital, U.K.
J Am Acad Dermatol. 1992 Apr;26(4):590-3. doi: 10.1016/0190-9622(92)70086-u.
Rosacea is a common facial eruption that has various clinical presentations.
We studied blood flow in lesional skin and explored the role of Demodex folliculorum in patients with rosacea.
A survey of clinical presentations was made in 108 patients with rosacea. Facial blood flow was studied by laser-Doppler flowmetry. The presence of Demodex was determined by microscopy of skin samples.
The sex incidence was equal. The incidence peaked in the fourth and seventh decades of life. Lymphedema was common and was seen in 26 patients. Rhinophyma was present in 15 patients, mostly men. Eleven patients were black, an unexpectedly high number. Laser-Doppler flowmetry showed that lesional blood flow was three to four times that of control subjects. Demodex folliculorum was found in 20 of 25 rosacea patients examined but in only 2 of 20 control subjects.
The findings indicate that the papillary dermal vasculature is dilated in rosacea. Demodex may be present. These findings give no definitive clue as to the origin of the disease.
酒渣鼻是一种常见的面部皮疹，有多种临床表现。
我们研究了酒渣鼻患者皮损部位的血流情况，并探讨了毛囊蠕形螨在其中的作用。
对108例酒渣鼻患者的临床表现进行了调查。采用激光多普勒血流仪研究面部血流情况。通过皮肤样本显微镜检查确定毛囊蠕形螨的存在。
男女发病率相等。发病率在40岁和70岁时达到高峰。淋巴水肿很常见，26例患者出现该症状。15例患者出现鼻赘，多数为男性。11例患者为黑人，数量出乎意料地高。激光多普勒血流仪显示，皮损部位的血流是对照受试者的三到四倍。在25例接受检查的酒渣鼻患者中，20例发现有毛囊蠕形螨，而在20例对照受试者中只有2例发现。
研究结果表明，酒渣鼻患者真皮乳头层血管扩张。可能存在毛囊蠕形螨。这些发现并未明确该病的病因。
