Bouderka Moulay Ahmed, Fakhir Bouchra, Bouaggad Abderrahmane, Hmamouchi Badreddine, Hamoudi Driss, Harti Abdeslam
Department of Anesthesiology and Intensive Care Unit (P33), Ibn Rochd Hospital, Casablanca, Morocco.
J Trauma. 2004 Aug;57(2):251-4. doi: 10.1097/01.ta.0000087646.68382.9a.
To see if early tracheostomy (fifth day) reduces duration of mechanical ventilation, ICU stay, incidence of pneumonia and mortality in comparison with prolonged intubation (PI) in patients with head injury.
Patients were prospectively included in this study if they met the following criteria: isolated head injury, Glasgow coma scale (GCS) score < or =8 on first and fifth day, with cerebral contusion on CT scan. On the fifth day, randomization was done in two groups: early tracheostomy group (T group, n = 31) and prolonged endotracheal intubation group (I group, n = 31). We evaluated total time of mechanical ventilation, ICU stay, pneumonia incidence and mortality. Complications related to each technique were noted. Analysis of data were performed using Yates and Kruskall Walis tests. p < 0.05 was considered significant.
The two groups were comparable in term of age, sex, and Simplified Acute Physiologic Score (SAPS). The mean time of mechanical ventilatory support was shorter in T group (14.5 +/- 7.3) versus I group (17.5 +/- 10.6) (p = 0.02). After pneumonia was diagnosed, mechanical ventilatory time was 6 +/- 4.7 days for ET group versus 11.7 +/- 6.7 days for PEI group (p = 0.01). There was no difference in frequency of pneumonia or mortality between the two groups.
In severe head injury early tracheostomy decreases total days of mechanical ventilation or mechanical ventilation time after development of pneumonia.
观察与延长气管插管(PI)相比,早期气管切开术(第5天)是否能缩短颅脑损伤患者的机械通气时间、重症监护病房(ICU)住院时间、肺炎发生率及死亡率。
符合以下标准的患者前瞻性纳入本研究:单纯颅脑损伤,第1天和第5天格拉斯哥昏迷量表(GCS)评分≤8分,CT扫描显示脑挫裂伤。在第5天,将患者随机分为两组:早期气管切开组(T组,n = 31)和延长气管插管组(I组,n = 31)。我们评估了机械通气总时间、ICU住院时间、肺炎发生率及死亡率。记录与每种技术相关的并发症。使用Yates检验和Kruskall Wallis检验进行数据分析。p < 0.05被认为具有统计学意义。
两组在年龄、性别和简化急性生理评分(SAPS)方面具有可比性。T组机械通气支持的平均时间(14.5±7.3)短于I组(17.5±10.6)(p = 0.02)。肺炎诊断后,气管切开组机械通气时间为(6±4.7)天,延长气管插管组为(11.7±6.7)天(p = 0.01)。两组之间肺炎发生率或死亡率无差异。
在重度颅脑损伤中,早期气管切开可减少机械通气总天数或肺炎发生后的机械通气时间。