含活性陶瓷填料的聚甲基丙烯酸甲酯基复合材料：第三部分：含显影粒子增强骨水泥

PMMA-based composite materials with reactive ceramic fillers: part III: radiopacifying particle-reinforced bone cements.

作者信息

Abboud M, Vol S, Duguet E, Fontanille M

机构信息

Institut de Chimie de la Matière Condensée de Bordeaux, CNRS, avenue du Docteur Albert Schweitzer, F-33608 Pessac Cedex, France.

出版信息

J Mater Sci Mater Med. 2000 May;11(5):295-300. doi: 10.1023/a:1008981917653.

DOI:10.1023/a:1008981917653

PMID:15348026

Abstract

New acrylic bone cements were prepared from alumina particles previously treated by 3-(trimethoxysilyl)propylmethacrylate (gamma-MPS), able to act both as radiopacifying and reinforcing agents. The present study deals with the handling characteristics and the compressive behavior of such cements. The influence of the particles morphology, their surface-modification by gamma-MPS bonding agent, their concentration in the cement, the powder-to-liquid ratio and the benzoyl peroxide concentration are reported. The role of grafted gamma-MPS molecules as coupling agent was confirmed. For several formulations, compressive strength and modulus reached 150 MPa and 3400 MPa respectively. Limitations in the use of such formulations are also comprehensively discussed.

摘要

新型丙烯酸骨水泥由先前用甲基丙烯酸3-(三甲氧基甲硅烷基)丙酯（γ-MPS）处理过的氧化铝颗粒制备而成，γ-MPS既能作为射线不透光剂，又能作为增强剂。本研究探讨了此类骨水泥的操作特性和压缩性能。报告了颗粒形态、γ-MPS粘结剂对其表面的改性、它们在骨水泥中的浓度、粉液比以及过氧化苯甲酰浓度的影响。证实了接枝的γ-MPS分子作为偶联剂的作用。对于几种配方，抗压强度和模量分别达到了150MPa和3400MPa。还全面讨论了此类配方使用中的局限性。