Tipper J L, Firkins P J, Ingham E, Fisher J, Stone M H, Farrar R
Department of Microbiology, University of Leeds, Leeds, LS2 9JT, UK.
J Mater Sci Mater Med. 1999 Jun;10(6):353-62. doi: 10.1023/a:1026473723777.
The biological reactions to polyethylene wear debris have been shown to result in osteolysis and loosening of total hip arthroplasties. This has led to renewed interest in the use of metal on metal bearings in hip prostheses. This study employed uniaxial and biaxial multistation pin on plate reciprocators to assess how the carbon content of the cobalt chrome alloy and the types of motion affected the wear performance of the bearing surfaces and the morphology of the wear debris generated. The low carbon specimens demonstrated higher wear factors than both the mixed carbon pairings and the high carbon pairings. The biaxial motion decreased the wear rates of all specimens. Plate wear was significantly reduced by the biaxial motion, compared to pin wear. The metal wear particles isolated were an order of magnitude smaller than polyethylene particles, at 60-90 nm, and consequently, 100-fold more particles were produced per unit volume of wear compared to polyethylene. The low carbon specimens produced significantly larger particles than the other material combinations, although it is thought unlikely that the difference would be biologically significant in vivo. The volumetric wear rates were affected by the carbon content of the cobalt chrome alloy, the material combination used and type of motion applied. However, particle morphology was not affected by the carbon content of the alloy or the type of motion applied.
对聚乙烯磨损颗粒的生物反应已被证明会导致全髋关节置换术的骨溶解和假体松动。这使得人们对髋关节假体中金属对金属轴承的使用重新产生兴趣。本研究采用单轴和双轴多工位销盘往复试验机，以评估钴铬合金的碳含量和运动类型如何影响轴承表面的磨损性能以及所产生磨损颗粒的形态。低碳试样的磨损系数高于混合碳配对和高碳配对。双轴运动降低了所有试样的磨损率。与销磨损相比，双轴运动显著降低了盘的磨损。分离出的金属磨损颗粒比聚乙烯颗粒小一个数量级，为60 - 90纳米，因此，每单位磨损体积产生的颗粒数量比聚乙烯多100倍。低碳试样产生的颗粒明显大于其他材料组合，尽管人们认为这种差异在体内不太可能具有生物学意义。体积磨损率受钴铬合金的碳含量、所用材料组合和施加的运动类型影响。然而，颗粒形态不受合金碳含量或施加的运动类型影响。
