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儿童脑干脓肿

Brain stem abscesses in childhood.

作者信息

Suzer T, Coskun E, Cirak B, Yagci B, Tahta K

机构信息

Department of Neurosurgery, Pamukkale University Hospital, 20100 Denizli, Turkey.

出版信息

Childs Nerv Syst. 2005 Jan;21(1):27-31. doi: 10.1007/s00381-004-1024-1. Epub 2004 Sep 2.

Abstract

BACKGROUND

Solitary brain stem abscess is a rare condition with high mortality and morbidity. These lesions were considered to be invariably fatal before 1974 when advanced diagnostic tools were not available. Recently, the diagnosis and prognosis of brain stem abscesses have been modified by the introduction of modern radiological tools, and several patients with a favorable outcome have been reported since then. Because the pons is the most common site of the abscesses, involvement of the sixth and seventh nerves is frequent. The midbrain is the second most likely location, and medullary abscesses are distinctly rare. Treatment of a brain stem abscess includes medical therapy alone, open microsurgical intervention, or stereotactic aspiration.

CASE REPORT

We report a case of a 7-year-old girl with a solitary brain stem abscess. Her neurological examination revealed involvement of the cranial nerves and pyramidal tracts. Microsurgical exposure and aspiration of the abscess resulted in rapid improvement in her neurological condition and radiological resolution of the lesion. We discuss this uncommon case to draw attention to the importance of early diagnosis and adequate treatment, and we review the relevant literature.

摘要

背景

孤立性脑干脓肿是一种罕见疾病,死亡率和发病率都很高。在1974年先进诊断工具尚未出现之前,这些病变被认为必然是致命的。最近,随着现代放射学工具的引入,脑干脓肿的诊断和预后已有所改变,此后已有数例患者取得了良好的治疗效果。由于脑桥是脓肿最常见的部位,因此第六和第七神经受累很常见。中脑是第二常见的发病部位,而延髓脓肿则极为罕见。脑干脓肿的治疗方法包括单纯药物治疗、开放性显微手术干预或立体定向穿刺抽吸。

病例报告

我们报告一例7岁女童患有孤立性脑干脓肿的病例。她的神经系统检查显示颅神经和锥体束受累。对脓肿进行显微手术暴露和抽吸后,她的神经状况迅速改善,病变在影像学上也得到消退。我们讨论这一罕见病例,以引起对早期诊断和充分治疗重要性的关注,并对相关文献进行综述。

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