Anter A M, Bondok R S
Department of Anaesthesiology, Ain-Shams University Hospital, Cairo, Egypt.
Acta Anaesthesiol Scand. 2004 Oct;48(9):1101-4. doi: 10.1111/j.1399-6576.2004.00503.x.
Peripheral venous pressure (PVP) is easily and safely measured. In adults, PVP correlates closely with central venous pressure (CVP) during major non-cardiac surgery. The objective of this study was to evaluate the agreement between CVP and PVP in children during major surgery and during recovery.
Fifty patients aged 3-9 years, scheduled for major elective surgery, each underwent simultaneous measurements of CVP and PVP at random points during controlled ventilation intraoperatively (six readings) and during spontaneous ventilation in the post-anaesthesia care unit (three readings). In a subset of four patients, measurements were taken during periods of hypotension and subsequent fluid resuscitation (15 readings from each patient).
Peripheral venous pressure was closely correlated to CVP intraoperatively, during controlled ventilation (r=0.93), with a bias of 1.92 (0.47) mmHg (95% confidence interval = 2.16-1.68). In the post-anaesthesia care unit, during spontaneous ventilation, PVP correlated strongly with CVP (r = 0.89), with a bias of 2.45 (0.57) mmHg (95% confidence interval = 2.73-2.17). During periods of intraoperative hypotension and fluid resuscitation, within-patient changes in PVP mirrored changes in CVP (r = 0.92).
In children undergoing major surgery, PVP showed good agreement with CVP in the perioperative period. As changes in PVP parallel, in direction, changes in CVP, PVP monitoring may offer an alternative to direct CVP measurement for perioperative estimation of volume status and guiding fluid therapy.
外周静脉压(PVP)易于且安全地测量。在成年人中,重大非心脏手术期间外周静脉压与中心静脉压(CVP)密切相关。本研究的目的是评估儿童在重大手术及恢复期间中心静脉压与外周静脉压之间的一致性。
50例年龄在3至9岁、计划接受重大择期手术的患者,在术中控制通气期间(六个读数)以及麻醉后护理单元自主通气期间(三个读数)的随机时间点同时测量中心静脉压和外周静脉压。在一个由四名患者组成的亚组中,在低血压期及随后的液体复苏期间进行测量(每位患者15个读数)。
术中控制通气期间,外周静脉压与中心静脉压密切相关(r = 0.93),偏差为1.92(0.47)mmHg(95%置信区间 = 2.16 - 1.68)。在麻醉后护理单元自主通气期间,外周静脉压与中心静脉压高度相关(r = 0.89),偏差为2.45(0.57)mmHg(95%置信区间 = 2.73 - 2.17)。在术中低血压和液体复苏期间,患者外周静脉压的变化反映了中心静脉压的变化(r = 0.92)。
在接受重大手术的儿童中,外周静脉压在围手术期与中心静脉压显示出良好的一致性。由于外周静脉压的变化在方向上与中心静脉压的变化平行,外周静脉压监测可为围手术期容量状态评估和指导液体治疗提供一种替代直接测量中心静脉压的方法。