Sherif Lulu, Joshi Vikas S, Ollapally Anjali, Jain Prithi, Shetty Kishan, Ribeiro Karl Sa
Department of Anaesthesiology, Fr. Muller Medical College, Mangalore, Karnataka, India.
Indian J Crit Care Med. 2015 Apr;19(4):199-202. doi: 10.4103/0972-5229.154548.
Optimizing cardiovascular function to ensure adequate tissue oxygen delivery is a key objective in the care of critically ill patients with burns. Hemodynamic monitoring may be necessary to optimize resuscitation in serious burn patients with reasonable safety. Invasive central venous pressure (CVP) monitoring has become the corner stone of hemodynamic monitoring in patients with burns but is associated with inherent risks and technical difficulties. Previous studies on perioperative patients have shown that measurement of peripheral venous pressure (PVP) is a less invasive and cost-effective procedure and can reliably predict CVP.
The aim of the present prospective clinical study was to determine whether a reliable association exists between changes in CVP and PVP over a long period in patients admitted to the Burns Intensive Care Unit (BICU).
The CVP and PVP were measured simultaneously hourly in 30 burns patients in the BICU up to 10 consecutive hours. The predictability of CVP by monitoring PVP was tested by applying the linear regression formula and also using the Bland-Altman plots of repeated measures to evaluate the agreement between CVP and PVP.
The regression formula revealed a reliable and significant association between CVP and PVP. The overall mean difference between CVP and PVP was 1.628 ± 0.84 mmHg (P < 0.001). The Bland-Altman diagram also showed a perfect agreement between the two pressures throughout the 10 h period.
Peripheral venous pressure measured from a peripheral intravenous catheter in burns patients is a reliable estimation of CVP, and its changes have good concordance with CVP over a long period of time.
优化心血管功能以确保充足的组织氧输送是烧伤重症患者护理的关键目标。对于严重烧伤患者,进行血流动力学监测可能有助于在合理安全的前提下优化复苏方案。有创中心静脉压(CVP)监测已成为烧伤患者血流动力学监测的基石,但它存在固有风险和技术难题。先前针对围手术期患者的研究表明,测量外周静脉压(PVP)是一种侵入性较小且性价比高的方法,并且能够可靠地预测中心静脉压。
本前瞻性临床研究旨在确定烧伤重症监护病房(BICU)患者在较长时间内中心静脉压(CVP)变化与外周静脉压(PVP)变化之间是否存在可靠的关联。
对30例入住BICU的烧伤患者每小时同时测量中心静脉压(CVP)和外周静脉压(PVP),持续10小时。通过应用线性回归公式以及使用重复测量的Bland-Altman图来评估CVP与PVP之间的一致性,从而测试通过监测PVP预测CVP的能力。
回归公式显示CVP与PVP之间存在可靠且显著的关联。CVP与PVP的总体平均差值为1.628±0.84 mmHg(P<0.001)。Bland-Altman图也显示在整个10小时期间两种压力之间具有完美的一致性。
烧伤患者外周静脉导管测量的外周静脉压是中心静脉压的可靠估计值,其变化在较长时间内与中心静脉压具有良好的一致性。