Cho Gae Young, Rémy Pauline, Jansson Jenny, Moessner Christian, Bolm Carsten
Institute of Organic Chemistry, RWTH Aachen University, Professor-Pirlet-Str. 1, D-52056 Aachen, Germany.
Org Lett. 2004 Sep 16;6(19):3293-6. doi: 10.1021/ol048806h.
[reaction: see text] Copper-mediated cross-coupling reactions of sulfoximines with aryl iodides and aryl bromides provide N-arylated sulfoximines in high yields. The method is complementary to the known palladium-catalyzed N-arylation and allows the preparation of N-arylated sulfoximines, which have previously been inaccessible.
[反应:见正文] 亚砜亚胺与芳基碘化物和芳基溴化物的铜介导交叉偶联反应能高产率地提供N-芳基化亚砜亚胺。该方法是对已知钯催化N-芳基化反应的补充,并且能够制备此前无法获得的N-芳基化亚砜亚胺。