Lee Jae-Bong, Kim Byung-Soo, Kim Moon-Bum, Oh Chang-Keun, Jang Ho-Sun, Kwon Kyung-Sool
Department of Dermatology, College of Medicine, Pusan National University, Busan, Korea.
Dermatol Surg. 2004 Sep;30(9):1233-5. doi: 10.1111/j.1524-4725.2004.30382.x.
Genital odor is an uncommon condition characterized by an offensive and malodorous smell in the genital area. Although the etiology of foul genital odor is multifactorial, an important cause is sweat secretion and decomposition of sweat components by bacteria. Different methods are effective in reducing body odor secondary to bromhidrosis. Conservative methods only act for a short period of time, and more invasive surgical methods carry risk of complications or are inapplicable for the genital region.
A patient with localized foul odor in the genital hair bearing area was treated with botulinum toxin A.
Botulinum toxin A was effective in creating an odorless and anhydrous response in the genital region, and no major adverse effects were noted during a follow-up of 9 months after injection.
Local injection of botulinum toxin A appears to be a useful treatment for foul genital odor related to sweat glands activity.
生殖器异味是一种罕见病症，其特征为生殖器区域出现令人不快的恶臭气味。尽管恶臭生殖器异味的病因是多因素的，但一个重要原因是汗液分泌以及细菌对汗液成分的分解。不同方法对于减轻由臭汗症引起的体臭有效。保守方法仅能在短时间内起作用，而更具侵入性的手术方法存在并发症风险或不适用于生殖器区域。
对一名生殖器毛发区域局部有异味的患者使用A型肉毒杆菌毒素进行治疗。
A型肉毒杆菌毒素有效地在生殖器区域产生了无气味且无水的反应，并且在注射后9个月的随访期间未观察到重大不良反应。
局部注射A型肉毒杆菌毒素似乎是治疗与汗腺活动相关的恶臭生殖器异味的一种有效方法。
