Hyperhidrosis clinic, Andreas Sygros Hospital, Athens, Greece.
J Cosmet Dermatol. 2011 Mar;10(1):74-7. doi: 10.1111/j.1473-2165.2010.00536.x.
Bromhidrosis is a common problem with a severe negative impact on the patient's social and emotional life. The objective of this open-label study was to evaluate the efficacy and safety of a local product with the main active ingredient of glycine-soja sterocomplex in the treatment of local bromhidrosis.
PATIENTS/METHODS: Eighteen patients with axillary bromhidrosis and eight patients with bromhidrosis of the genital area were included. Bromhidrosis was evaluated through a sniff test of a worn garment on a four-point scale. Patients applied a glycine-soja sterocomplex topical agent twice daily on the affected areas for 15 days and bromhidrosis was evaluated again.
Subjective mean level of bromhidrosis at baseline was 3.50 ± 0.50 and after treatment 1.53 ± 0.51. Mean impact on quality of life at baseline was 3.30 ± 0.48 and after treatment 1.30 ± 0.49. Investigators objective evaluation revealed an improvement in intensity of odor from 3.23 ± 0.83 to 1.53 ± 0.53 and in acceptability of odor from 3.1 ± 1.01 to 1.65 ± 0.76.
The glycine-soja sterocomplex topical agent shows encouraging improvement on both the intensity and quality of odor in patients with bromhidrosis and has a profound improvement on the patients' quality of life without any side effects.
狐臭是一种常见的问题，对患者的社交和生活产生严重的负面影响。本开放性研究的目的是评估一种含有主要活性成分甘氨酸-大豆甾醇复合物的局部产品治疗局部狐臭的疗效和安全性。
患者/方法：纳入 18 名腋窝狐臭患者和 8 名生殖器区域狐臭患者。通过对穿着的衣物进行嗅探测试，对狐臭进行四级评估。患者每天在受影响的区域涂抹两次甘氨酸-大豆甾醇复合物局部制剂，持续 15 天，然后再次评估狐臭。
基线时狐臭的主观平均水平为 3.50 ± 0.50，治疗后为 1.53 ± 0.51。基线时对生活质量的平均影响为 3.30 ± 0.48，治疗后为 1.30 ± 0.49。研究者的客观评估显示，气味强度从 3.23 ± 0.83改善至 1.53 ± 0.53，气味可接受度从 3.1 ± 1.01改善至 1.65 ± 0.76。
甘氨酸-大豆甾醇复合物局部制剂可显著改善狐臭患者的气味强度和质量，对患者的生活质量有明显改善，且无任何副作用。
