Felius Joost, Stager David R, Berry Priscilla M, Fawcett Sherry L, Stager David R, Salomão Solange R, Berezovsky Adriana, Birch Eileen E
Retina Foundation of the Southwest, 9900 N. Central Expressway, Dallas, TX 75231, USA.
Am J Ophthalmol. 2004 Sep;138(3):362-72. doi: 10.1016/j.ajo.2004.05.010.
Quality of life (QOL) instruments are increasingly utilized in ophthalmological research. Measuring vision-related QOL in young children is complicated by constantly evolving abilities related to normal growth and development. Our aim was to develop vision-related QOL instruments for children in different age ranges <==7 years, and to provide initial validation of these instruments.
Cross-sectional study.
Multicenter.
773 pediatric patients (age <==7 years) with a wide range of ophthalmological diagnoses.
Questionnaire. A 61-item prototype instrument with a wide variety of items was applied to 403 consecutive patients. The usefulness of items was evaluated as a function of age in order to derive two age-group specific instruments and to find the age limit dividing the age groups. Thus, age-specific versions of a Children's Visual Function Questionnaire (CVFQ) were defined for ages <3 years and >/=3 years, and applied to a convenience sample of patients.
Subscale scores. Factor analysis helped identify underlying dimensions of the data, and corresponding subscales were defined. Validation was provided by examining the internal consistency reliability and by exploring the associations between scores and clinical characteristics.
Subscales for General health, General vision, Competence, Personality, Family impact, and Treatment were defined, with internal consistency reliabilities ranging from 0.60 to 0.86. The association between subscales scores and age was weak, whereas strong correlations were found with the level of visual impairment and type of visual diagnosis.
The CVFQ assesses the impact of visual impairment on children and their families, and is expected to become a useful tool for the pediatric vision research community.
生活质量（QOL）工具在眼科研究中的应用日益广泛。由于与正常生长发育相关的能力不断发展，测量年幼儿童与视力相关的生活质量变得复杂。我们的目的是为不同年龄范围（≤7岁）的儿童开发与视力相关的生活质量工具，并对这些工具进行初步验证。
横断面研究。
多中心。
773例患有各种眼科疾病的儿科患者（年龄≤7岁）。
问卷调查。将一个包含61个项目的具有多种条目的原型工具应用于403例连续患者。根据年龄评估项目的有用性，以得出两个针对特定年龄组的工具，并找出划分年龄组的年龄界限。因此，为3岁以下和≥3岁的儿童定义了儿童视觉功能问卷（CVFQ）的特定年龄版本，并应用于便利样本患者。
分量表得分。因子分析有助于确定数据的潜在维度，并定义相应的分量表。通过检查内部一致性信度以及探索得分与临床特征之间的关联来进行验证。
定义了一般健康、一般视力、能力、性格、家庭影响和治疗等分量表，内部一致性信度范围为0.60至0.86。分量表得分与年龄之间的关联较弱，而与视力损害程度和视觉诊断类型之间存在强相关性。
CVFQ评估视力损害对儿童及其家庭的影响，有望成为儿科视力研究领域的有用工具。
