Skerk Visnja, Krhen Ivan, Schonwald Slavko, Cajic Vjeran, Markovinovic Leo, Roglic Srdan, Zekan Sime, Andracevic Arjana Tambic, Kruzic Vladimira
University Hospital for Infectious Diseases, Dr Fran Mihaljevic, Mirogojska 8, 10000 Zagreb, Croatia.
Int J Antimicrob Agents. 2004 Sep;24 Suppl 1:S53-6. doi: 10.1016/j.ijantimicag.2004.02.010.
A total of 1442 patients with symptoms of chronic prostatitis were examined over a 4-year period at the Outpatient Department for Urogenital Infections, University Hospital for Infectious Diseases "Dr. Fran Mihaljevic", Zagreb, Croatia. An infectious aetiology was determined in 1070 (74.2%) patients. In 561 of 1070 (52.4%) patients the inflammatory finding (>10 WBC/hpf) was found in expressed prostatic secretions (EPS) or voided bladder urine (VB(3)). Normal, <10 WBCs/hpf was found in 362 of 536 (67.5%) patients with symptoms of chronic prostatitis in whom Chlamydia trachomatis was detected in EPS or VB(3), in 51 of 151 (33.8%) patients with isolated Trichomonas vaginalis and in 40 of 72 (55.6%) patients with isolated Ureaplasma urealyticum. Escherichia coli was the causative pathogen in 95, Enterococcus in 68, Proteus mirabilis in 37, Klebsiella pneumoniae in 16, Streptococcus agalactiae in 19, and Pseudomonas aeruginosa in 3 patients with chronic prostatitis. Other patients had a mixed infection. In patients with chronic bacterial prostatitis (CBP) caused by E. coli, P. mirabilis, K. pneumoniae, E. or S. agalactiae, an inflammatory finding was regularly found in EPS or VB(3).
在克罗地亚萨格勒布“弗兰·米哈列维奇博士”传染病大学医院泌尿生殖感染门诊，对1442例有慢性前列腺炎症状的患者进行了为期4年的检查。1070例（74.2%）患者确定有感染性病因。在1070例患者中的561例（52.4%），在前列腺按摩液（EPS）或中段尿（VB(3)）中发现炎症表现（>10个白细胞/高倍视野）。在EPS或VB(3)中检测到沙眼衣原体的536例有慢性前列腺炎症状的患者中，362例（67.5%）白细胞正常，<10个/高倍视野；在151例单纯感染阴道毛滴虫的患者中，51例（33.8%）白细胞正常；在72例单纯感染解脲脲原体的患者中，40例（55.6%）白细胞正常。大肠杆菌是95例慢性前列腺炎患者的致病病原体，肠球菌68例，奇异变形杆菌37例，肺炎克雷伯菌16例，无乳链球菌19例，铜绿假单胞菌3例。其他患者为混合感染。在由大肠杆菌、奇异变形杆菌、肺炎克雷伯菌、无乳链球菌或B群链球菌引起的慢性细菌性前列腺炎（CBP）患者中，EPS或VB(3)中经常发现炎症表现。
